Diclofenac injections belong to the group of anti-inflammatory non-steroid drugs. The medication is used to reduce pain and the intensity of the inflammatory process, as well as for various pathological diseases in the structures of the musculoskeletal system.
Structure
The solution for intravenous administration of beneficial microorganisms necessary for the body in liquid form is a clear or yellow liquid. In one milliliter of the solution contains twenty-five milligrams of the active active ingredient - diclofenac sodium. And also in the composition of injections "Diclofenac" included additional trace elements, which include:
- Trilon B.
- Polyethylene Glycol-400.
- Acetylcysteine.
- Propylene glycol.
- Caustic soda.
- Water.
The drug is made in glass ampoules with a volume of three milliliters with an active substance content of seventy-five milligrams. The drug is packaged in contour cells of five pieces. The pack contains one contour package, as well as instructions for use.
Act
The active microelement of the Diclofenac solution (in ampoules) belongs to the group of nonsteroidal anti-inflammatory drugs. Its therapeutic effect is to suppress the functions of the cyclooxygenase enzyme. This enzyme accelerates the transformation of omega-6 unsaturated fatty acids into biologically active compounds of inflammatory response mediators. Namely, leukotrienes and prostacyclin. Due to a decrease in their concentration in the area of inflammation, the active substance has the following effects on the body:
- A decrease in the power of the pain syndrome resulting from direct irritation of the nerve endings by inflammatory mediators.
- Reducing the intensity of blood vessel filling in the problem area.
- The weakening of tissue swelling, which develops when exposed to mediators of infection on the vascular wall. What contributes to an increase in its permeability and the exit of lymph from the vascular bed into the component of connective tissue.
- Reducing the intensity of platelet adhesion, leading to a decrease in blood coagulation.
According to the instructions, Diclofenac injections in ampoules reduce the accumulation of prostaglandins of the digestive mucosa, which leads to a weakening of the resistance of the walls of the stomach and duodenum to any irritating conditions. In diseases of the musculoskeletal system, the main trace element helps reduce tissue swelling, pain, a sense of paralysis when moving in the joints.
After administration of the drug intramuscularly, diclofenac sodium is absorbed into the bloodstream within fifteen minutes. It spreads in the tissues of the body, the maximum amount of the drug accumulates in the structures of the musculoskeletal system. The half-life (the time during which half the entire dose of the drug is excreted from the body) is approximately three hours. What do Diclofenac injections help from?
Indications
The use of Diclofenac injection solution is necessary in case of malfunctions in the body, which are accompanied by inflammatory processes and pain syndromes. These include:
- Inflammatory or degenerative-dystrophic disease of the spine (metabolic failure in the cells of the spine, leading to tissue nutrient deficiency).
- Osteochondrosis (a chronic disease that affects the cartilage of the intervertebral discs).
- Protrusion (a pathological condition of the intervertebral disc, in which it protrudes beyond the vertebrae to a distance of not more than 5 millimeters).
- Hernias of the intervertebral discs (a disease of the human musculoskeletal system associated with displacement of the pulpous nucleus of the intervertebral disc with rupture of the fibrous ring).
- Sciatica (an inflammatory process that affects the sciatic nerve, sciatic nerve neuritis).
- Lumbago (an acute disease of a discogenic nature that occurs against a background of degenerative processes).
- Arthritis (collective designation of any joint disease).
- Disease of tissues of the internal environment with a major lesion of small joints.
- A disease that affects the entire body, crystals of sodium and potassium salts are deposited in various tissues.
- Osteoarthritis (degenerative joint disease caused by damage to the cartilage of the articular surfaces).
- Extraarticular rheumatism (a disease bordering on the affected joint).
- Post-traumatic pain.
- A feeling of discomfort and pain after hard physical work.
- Neuralgia (damage to the peripheral nerves, characterized by bouts of pain in the innervation zone of a nerve).
- Inflammation of the conditionally secreted part of the nervous system located outside the brain and spinal cord, in which, along with pain, a decrease in sensitivity appears.
- Postoperative pain syndrome.
According to indications, Diclofenac injections are used in the symptomatic treatment of renal or liver failure.
Contraindications
There are some prohibitions on the use of the drug for intravenous, intramuscular administration. Contraindications include:
- Individual intolerance to diclofenac sodium or additional trace elements of the drug.
- Peptic ulcer (local mucosal defect formed under the influence of hydrochloric acid).
- Chronic recurrent disease of the duodenum, which occurs with periods of exacerbation and remission.
- Failure of hematopoiesis in the red bone marrow.
- Bleeding from the stomach and intestines while using the medication.
- Hemophilia (a rare hereditary disease associated with a violation of the coagulation process).
- Pregnancy.
- Age restriction, the drug should not be prescribed to children under the age of fifteen.
With extreme caution, the drug is administered to a person who has pathologies in the digestive system, including a large intestine ulcer. As well as a malfunction in the liver and kidneys, porphyrin disease, systemic lupus erythematosus, a systematic increase in blood pressure, heart failure. Also not recommended for the treatment of the elderly. Before you start using Diclofenac injections, you should make sure that there are no listed contraindications.
Instruction manual
Diclofenac injections are intramuscularly injected into the outer, upper portion of the buttock. In this case, the needle is inserted deeply. The maximum therapeutic dosage of the drug is seventy-five milligrams (one ampoule per day). With severe pain, the introduction of two ampoules into different buttocks is allowed with a time interval of twenty or thirty minutes. The duration of therapy is two or three days, the need for continued treatment is prescribed by the attending doctor. It is allowed to combine the solution for injection with medicines for external use (gel, ointment), which contain diclofenac sodium as an active trace element.
How to give injections?
When it comes to acute pain, you need to act right away. Intravenous injections "Diclofenac" is administered strictly in a medical institution in a hospital setting. To do this, dissolve the solution in not less than one hundred milliliters of buffered sodium chloride. Intramuscular injections can be done by anyone at home.
In order for the drug to be absorbed into the blood as quickly as possible, and the solution does not cause pain, the ampoule before injection is heated in the palms to body temperature. The patient is best placed on the side before the procedure, so you can achieve maximum muscle relaxation. How to make diclofenac injections?
Having collected the solution in the syringe, turn it over and push all the air out of the syringe, slowly pressing the piston, until a droplet appears on the end of the needle. Subcutaneous administration is unacceptable.
Use the drug "Diclofenac" once a day. At least a day should pass before the next injection, sometimes the drug is alternated with injections of Analgin. One, two ampoules are often enough, although the course of treatment in some situations can last quite a long time.
Before you start the injection, you need to thoroughly wash your hands, disinfect them and the injection site with ethyl alcohol. The tip of the ampoule should also be treated with alcohol. In order for the drug to fall down, you need to lightly tap it with your fingernail. What do Diclofenac injections help from?
How to stab Diclofenac for back and lower back pain?
The main advantages of using the drug for pain in the back, joints of the legs and arms are its high analgesic activity, good antimicrobial effect and a fairly short half-life.
The use of Diclofenac injections for back pain not only produces an analgesic effect, but also reduces morning stiffness and helps to increase the range of motion of the joints.
If swelling occurs after an injury, then with the help of this medication it instantly decreases. It is used for pain in the back of any etiology (bruise, contusion, dislocation).
You need to be mentally prepared for the fact that injections are painful enough. It is recommended to put them alternately in one buttock or in the other. How many do diclofenac injections do?
In most cases, with back pain, Diclofenac injections are given for the first few days, then other forms of drugs are used. In rare situations, the doctor may extend the injection therapy for up to five days.
Does the drug have side effects?
According to the instructions for Diclofenac injections, with an independent increase in the dose, the following negative effects in the digestive system can be observed:
- Acute or chronic pain in the abdomen that occurs periodically or is observed constantly.
- Pathological symptoms in which the patient has frequent bowel movements, while the stool becomes watery.
- Flatulence (excessive accumulation of gases in the intestines).
- Loss of appetite.
- The appearance of bleeding in the stomach or intestines.
- Stomatitis (damage to the oral mucosa).
- Sense of anxiety.
- Bad sleep and nightmares.
In addition, if you neglect the contraindications to Diclofenac injections, side effects will not take long. Visual and hearing impairment, tinnitus may occur. Also, hand tremors, increased cramps of skeletal muscles, paresthesia are possible.
From the side of hematopoiesis, the following side effects may appear:
- Poor blood coagulation.
- Thrombocytopenia (a condition characterized by a decrease in platelet count below 150 · 109 / l, which is accompanied by increased bleeding and problems with stopping bleeding).
- Leukopenia (a decrease in the number of leukocytes per unit volume of blood).
- Anemia (decrease in hemoglobin concentration in the blood).
When taking an increased dose, negative symptoms may appear in the urinary system:
- A disease characterized by chronic or acute inflammatory lesions of the renal tubules and interstitial tissue.
- Decreased kidney function.
- Hematuria (the presence of blood in the urine in excess of the values that make up the physiological norm).
In addition to these symptoms, some other disorders can be observed:
- Erythema (severe redness of the skin caused by the expansion of capillaries).
- Photodermatosis (an inflammatory process on the skin as a result of hypersensitivity to both direct and reflected sunlight).
- A disease in which the loss of existing ones and a violation of the process of new hair growth are characteristic.
- Pneumonitis or pulmonitis in another way (interstitial inflammation of the vascular wall of the alveoli, accompanied by scarring).
- Constant increase in blood pressure.
- Homeostasis of sodium and potassium in the body.
At the injection site, local inflammation may occur with reddening of the skin, pain and the occurrence of infiltrate. With the development of negative phenomena, drug treatment is stopped.
Diclofenac and alcohol compatibility
If the patient has consumed a strong drink, then taking the medicine is strictly prohibited. The effect of the medication received directly under the protective membrane of a person is toxic. Irreversible harm can be caused to the health of a patient who has taken alcohol.
How long after drinking alcohol can I get Diclofenac injections? According to reviews, it is known that no sooner than a couple of days, when the alcohol is completely "weathered". The active components of the drug interact with the blood in the body. If it contains ethyl alcohol or if you take alcohol after the injection, then all this can lead to serious negative consequences. Drinking alcohol is strictly prohibited.
Diclofenac, which is intended for injections, is capable of provoking edema and malfunction of the kidneys, migraine, and vomiting due to its side effects. The combined use of alcohol and Diclofenac causes acute renal failure, which, if untimely provided, can even lead to death.
Cervical osteochondrosis
Diclofenac injections in case of a disease, as a result of which the soft intervertebral pulp degenerates into ossified tissue, are used to inhibit the development of prostaglandin syntheses. Due to this, the severity of inflammation decreases, and the patient quickly recovers.
At the very beginning of the disease, the doctor sets small doses. They instantly suspend the inflammatory process and promote recovery. With more complex forms of the disease, the amount of the main active ingredient is increased.
According to the instructions, Diclofenac injections for osteochondrosis are administered strictly intramuscularly. The maximum daily dose is 150 milligrams of active substance. It is usually prescribed in especially advanced cases. Mostly use a dosage of seventy-five milligrams.
Price
The cost of injections "Diclofenac" is an average of 170 rubles per package. Shelf life is five years. The drug must be kept in a dark place at a temperature of no more than twenty-five degrees.
Analogs
Diclofenac injections have a number of substitute drugs:
- "Naklofen."
- Movalis.
- Dicloberl.
"Naklofen" - a non-steroidal anti-inflammatory drug, is available in the form of a solution of three milliliters (5 pieces in a blister). The current microelement is diclofenac sodium. The drug also has antipyretic and analgesic properties. As a rule, Naklofen is recommended for use for symptomatic treatment, which is aimed at achieving an instant analgesic effect.
The drug is prescribed with caution in coronary heart disease, cerebrovascular disorders, diabetes mellitus, smoking, hyperlipidemia. The solution is administered intramuscularly in a dosage of seventy-five milligrams. Reuse in renal failure is possible half an hour after the injection; in other diseases, the drug can be used only after twelve hours. The duration of therapy should not exceed two days. Naklofen cannot be mixed in the same syringe with other medicines. The cost of the medication is about 190 rubles.
"Movalis" is a non-steroidal medicine made in Spain and has anti-inflammatory and antipyretic effects. The drug is used to treat diseases of the musculoskeletal system, such as osteoarthrosis, rheumatoid arthritis. "Movalis" effectively eliminates the inflammatory process, pain, lowers high body temperature. The injections are intended for the rapid relief of pain and acute diseases of the musculoskeletal system. The maximum daily dosage varies from 7.5 to 15 milligrams, depending on the severity of the disease. The cost of the drug varies from 480 to 550 rubles.
"Dicloberl" is an anti-inflammatory drug whose active ingredient is diclofenac sodium. The drug effectively relieves fever, swelling. Injections are made intramuscularly, the daily dosage should be no more than 150 milligrams. As a rule, injections are prescribed for colic and non-articular rheumatism. The tool effectively manifests its effect in migraines and pain of various origins.
The positive reviews left by patients about Diclofenac injections claim that the drug perfectly eliminates pain and relieves fatigue.