The increased acidity of the gastric juice not only contributes to the appearance of discomfort, bloating and heaviness, but can also cause erosion or even an ulcer. Therefore, with the first symptoms of such a pathology, you should immediately consult a gastroenterologist.
Fortunately, today there are a huge number of different medicines that help lower the acidity of the gastric juice, and also solve a number of other problems associated with the digestive tract. One such drug is Omeprazole-Teva. Instructions for use, the manufacturer of this medicine will be presented below. You will also learn about how the medication mentioned works, what consumer reviews say about it, and more.
Composition, description and form of release
The drug "Omeprazole-Teva", the instruction of which is contained in a cardboard package, goes on sale in the form of opaque solid cellulose capsules No. 3. They have an orange body and a red lid. The letter “O” and the number 10, 20 or 40 are printed in white ink on them (depending on the dosage).
The contents of the capsules is white micropellets (may be pinkish or yellowish).
What does the omeprazole-teva medication contain? Instructions for use indicate that the active ingredient in this medication is omeprazole. As for the additional components, such substances as oleic acid, sugar grains, type A 2 sodium carboxymethyl starch, povidone, sodium lauryl sulfate, potassium oleate, hypromellose, triethyl citrate, methacrylic acid and ethyl acrylate copolymer, titanium dioxide and talc are used.
The composition of the cellulose capsule includes carrageenan, dye "sunset" yellow, potassium chloride, titanium dioxide, dye iron oxide red, hypromellose, water, dye red charming.
Pharmacological properties
What are omeprazole-teva capsules? Instructions for use claim that it is an inhibitor of K + -H + -ATPase. It slows down the activity of K + -H + -ATPase in the parietal cells of the stomach and blocks the secretion of hydrochloric acid. This effect of the drug helps to reduce the level of stimulated and basal secretion, regardless of the nature of the stimulus.
Due to a decrease in acid secretion, it ceases to have a detrimental effect on the esophagus of a patient with reflux esophagitis.
It should also be noted that omeprazole is able to have a bactericidal effect against Helicobacter pylori. The eradication of this bacterium while taking the drug and antibiotics at the same time allows you to instantly stop the signs of the disease, as well as achieve rapid healing of the damaged mucous membrane, prolonged remission and reduce the possible development of bleeding from the gastrointestinal tract.
Kinetics of medication
What kinetic properties does Omeprazole-Teva have? When taken orally, the medication is quickly absorbed from the gastrointestinal tract and penetrates the parietal cells of the stomach. Communication with plasma proteins is about 96% (mainly with albumin).
Biological transformation of the drug occurs in the liver. It is excreted by the kidneys (about 72-80%) and along with feces (about 20%).
The half-life of the drug is ½-1 hour. In people with chronic liver diseases, this period increases to 3 hours.
Medication "Omeprazole-Teva": indications for use
According to the instructions, the tool in question works well with:
- gastroesophageal reflux disease (or abbreviated GERD), reflux esophagitis, including the prevention of relapse;
- peptic ulcer (including for the prevention of relapse) of the duodenum and stomach;
- ulcerative and erosive lesions of the digestive tract (i.e. the duodenum and stomach), which are associated with Helicobacter pylori (as part of complex treatment);
- ulcerative and erosive lesions of the digestive tract (i.e. the duodenum and stomach), which are associated with NSAIDs;
- Zollinger-Ellison syndrome, as well as other pathological conditions that are associated with abnormal gastric secretion.
Contraindications
When should you not take Omeprazole-Teva? Reviews report that such a medicine is contraindicated in case of hypersensitivity to omeprazole or to any component of the drug. In addition, it cannot be prescribed for fructose intolerance, pregnancy, sucrose and isomaltose deficiency, lactation, glucose-galactose malabsorption, and at a minor age. Also, the medication is contraindicated in conjunction with Clarithromycin in people with liver failure, St. John's wort and Atazanavir.
With caution, the drug in question is prescribed for insufficient liver and kidney function.
The drug "Omeprazole-Teva." What is the cure? How to use?
Indications for this drug were presented above. To treat these diseases, the medication is taken only inside. Do this in the morning before breakfast or while eating. Capsules are washed down with plain water and are not chewed.
With exacerbation of gastrointestinal ulcer and reflux esophagitis, the drug is prescribed 20 mg once a day. The duration of treatment is 4-9 weeks. If necessary, the dose can be increased to 40 mg per day.
For maintenance therapy of GERD and the prevention of relapse, the medication is taken 10-20 mg for 25-55 weeks (depending on the clinical effect). In case of severe esophagitis, the drug is prescribed for life.
In the treatment of ulcerative and erosive lesions of the digestive tract, which are associated with the use of NSAIDs, as well as for the prevention of relapse, Omeprazole-Teva is recommended to take 10-20 mg per day.
Zollinger-Ellison syndrome should be treated only after consulting a doctor. The recommended starting dosage is 60 mg once a day. If required, then this amount is increased to 80-120 mg per day (divided into two doses).
How to eliminate Helicobacter pylori with Omeprazole-Teva? Instructions for use states that in this case, complex therapy is needed (along with antibiotics). The drug is taken in a dose of 20 mg twice a day for a week.
Side effects
What negative reactions occur after taking Omeprazole-Teva capsules? Reviews report that such a drug can cause:
- rash, allergic vasculitis, fever, narrowing of the bronchi, angioedema, fever and anaphylactic shock;
- hypochromic microcytic anemia, reversible thrombocytopenia, pancytopenia, leukopenia and agranulocytosis;
- headache, paresthesia, dizziness, lethargy, insomnia, confusion, drowsiness, hallucinations, anxiety and depression;
- impaired auditory perception, including tinnitus;
- visual disturbances, including a decrease in visual fields, clarity of visual perception and a decrease in visual acuity;
- nausea, discoloration of the tongue, vomiting, dry mouth, flatulence, stomatitis, constipation, candidiasis, diarrhea, abdominal pain, perversion of taste, benign salivary gland cysts, pancreatitis;
- pruritus, Stevens-Johnson syndrome, alopecia, erythema multiforme, photosensitivity, increased sweating, toxic epidermal necrolysis ;
- interstitial nephritis;
- changes in liver enzymes, hepatitis, encephalopathy, jaundice, liver failure;
- fractures of the vertebrae, femoral head and wrist bones, myalgia, muscle weakness and arthralgia;
- peripheral edema, hyponatremia, hypomagnesemia and gynecomastia.
Drug overdose
What will happen if the doses of Omeprazole-Teva are exceeded? The instructions for use report the following symptoms: confusion, blurred vision, increased sweating, drowsiness, headache, agitation, dry mouth, arrhythmia, nausea.
To eliminate such phenomena, symptomatic therapy is required.
Interaction with other drugs
What medicines should not be taken with omeprazole-teva capsules? When combined with Ketoconazole, absorption of the latter may decrease.
The drug in question reduces the absorption of vitamin B12 with prolonged use.
With simultaneous use with omeprazole, the excretion of Diazepam, Warfarin, and Phenytoin slows down.
Special recommendations
Before taking the drug "Omeprazole-Teva", the analogues of which are listed below, the presence of a malignant tumor in the upper gastrointestinal tract should be excluded. This is due to the fact that this medication can mask the symptoms and delay the diagnosis.
Reducing the acidity of gastric juice increases the number of bacteria in the digestive tract. This increases the risk of developing various infections.
The medication in question contains sodium. This must be taken into account for those who are on a controlled sodium diet.
Patients at high risk of developing osteoporosis during therapy are required to ensure adequate intake of vitamin D and calcium.
Similar means
The drug in question has many different analogues. These include Helikol, Lansofed, Pariet, Ontime, Nexium, Epicurus and others. Also, this medication can be replaced by one of the following synonyms: Omeprazole-Acre, Gastrozole, Zerocide, Omeprazole-STADA, Omez, Omitox, Omipix, Omizak, Promez, Omeprazole Richter, Helicid, Ultop, etc.
Omeprazole-Teva or Omeprazole: which is better? The answer to this question can only be given by an experienced pharmacist. According to experts, it is quite difficult to identify the best drug from the presented ones, since both of them effectively cope with the task.
Are there any differences between Omeprazole and Omeprazole-Teva? The difference between them is only in the manufacturer and price. The company that produces the drug in question is located in Spain and is called “Teva Pharma”.
Reviews
Now you know what properties are inherent in the medicine "Omeprazole-Teva". What heals, how to take this remedy, we also told above.
According to consumers, this drug is an effective, inexpensive and fast-acting drug that is used for GERD, exacerbation of peptic ulcers and other acid-dependent diseases of the digestive tract.
As for doctors, they also leave only positive reviews about omeprazole. Doctors say that this remedy has established itself as a very safe and effective medicine for short-term use in order to eliminate heartburn.