At what dose is the drug "Novalgin" prescribed? Instructions for use of the mentioned medicine will be presented below. Also in the materials of this article you will find information about what features are inherent in this medication, how much it costs, what patients say about it and what indications it is used for.
Composition, packaging, description and form
In what form is the drug "Novalgin" issued? The instructions for the medicine are placed in a cardboard box. The drug itself may be contained in blisters or in plastic containers.
Active components of Novalgin white biconvex tablets, reviews of which are mostly positive, are substances such as paracetamol, propiphenazone and caffeine. The drug also includes additional elements in the form of corn starch, magnesium stearate, lactose, microcrystalline cellulose, croscarmellose sodium and silicon dioxide.
Drug pharmacology
What is the medicine "Novalgin"? The instruction for use states that it is an analgesic, anti-inflammatory, psychostimulating and antipyretic agent. Its therapeutic effectiveness is due to the active elements that make up the drug.
Experts say that this medication is a combination medicine. Paracetamol has an antipyretic, mild anti-inflammatory and analgesic effect. It also slightly slows down the synthesis of prostaglandins and affects the thermoregulatory focus located in the hypothalamus.
Propiphenazone is an analgesic.
As for caffeine, it enhances the tone of the vessels of the brain and helps stimulate the respiratory and vasomotor centers. In addition, this substance reduces platelet aggregation and dilates the vessels of the muscles, heart and kidneys.
The fact that caffeine suppresses drowsiness and stimulates physical and mental performance is no secret to anyone.
Pharmacokinetics
Where is the drug Novalgin absorbed? The instruction reports that this tool is completely and fairly quickly absorbed from the digestive tract. The active substances of this medication react relatively weakly with plasma blood proteins. After using the medication, a small amount of paracetamol is converted into a highly active intermediate metabolite called N-acetyl-benzo-quinoneimine. It is inactivated by the glutathione system of cells.
Indications
When is the Novalgin medication prescribed? Reviews about this drug report that it is often used for:
- treatment of pain syndromes of medium and low intensity with dysmenorrhea (that is, painful menstruation, but in the absence of changes in the organic nature of the genital organs);
- febrile syndrome (used as an antipyretic agent);
- pain syndrome of medium and low intensity of various origins: migraine, headaches, toothache, myalgia, arthralgia and others.
Contraindications
When is it not recommended to use the drug "Novalgin"? Instructions for use indicate contraindications such as:
- glucose-6-phosphate dehydrogenase deficiency, acute hematoporphyria;
- insufficiency (heavy) work of the kidneys or liver, intracranial hypertension ;
- oppressed blood formation in the bone marrow, respiratory depression;
- bronchial asthma, alcohol intoxication;
- recurrent polyposis, arterial hypertension;
- intolerance to "Aspirin" or other anti-inflammatory non-steroidal agents, glaucoma;
- acute myocardial infarction, breastfeeding;
- arrhythmia, age up to 12 years;
- glucose-galactose malabsorption, pregnancy;
- lack of lactase, lactose intolerance;
- sensitization to drug substances.
With extreme caution, this drug is recommended to be used in old age, with peptic ulcer in the acute stage, moderate impairment of kidney or liver function, bronchial asthma.
The drug "Novalgin": instructions for use
The medication in question is taken only inside after eating, washed down with plain water.
For adult patients, this drug is prescribed in the amount of one or two tablets up to four times a day. The daily dosage of the drug should not be more than six tablets.
As for adolescents, they are recommended to take one tablet no more than 3 times a day.
The duration of this medication should not exceed three days when used as an antipyretic and five days as an anesthetic.
Side effects
Does the drug Novalgin cause adverse reactions? Instructions for use (the price of this medication is indicated below) indicates the following side effects:
- insomnia, irritability, dizziness, disorientation;
- skin hyperemia, skin rash, erythema, pruritus, urticaria, angioedema, bronchospasm, rhinorrhea, anaphylactic shock;
- vomiting, hepatonecrosis, nausea, increased activity of liver enzymes, abdominal pain, discomfort in the epigastric region;
- erythema multiforme exudative, toxic epidermal necrolysis;
- papillary necrosis, renal colic, interstitial nephritis;
- palpitations, increased pressure;
- neutropenia, leukopenia, sulfhemoglobinemia, methemoglobinemia, agranulocytosis, hemolytic anemia, pancytopenia, leukopenia, aplastic anemia, thrombocytopenia.
Drug overdose
With an overdose of paracetamol in patients, there is observed: pallor of the skin, anorexia, nausea, abdominal pain, vomiting, impaired glucose metabolism, impaired liver function, metabolic acidosis, liver failure, arrhythmia, encephalopathy, acute renal failure, coma, pancreatitis.
For the treatment of such conditions, donors of SH-groups are used, as well as precursors of the biological synthesis of glutathione-methionine and Acetylcysteine.
In case of overdose of caffeine in a patient, agitation, delirium, gastralgia, anxiety, motor anxiety, rapid urination, confusion, tinnitus, dehydration, nausea, tachycardia, tremor, hyperthermia, arrhythmia, increased pain sensitivity, headache, cramps, and cramps are noted: .
To eliminate such conditions, the patient is washed the stomach, give laxatives and enterosorbents.
Price, analogues
How much is the drug "Novalgin"? The price of such tablets varies between 210-230 rubles.
As for analogues, among them the following funds can be distinguished: “Rinza”, “Axagripp”, “Antiflu”, “Askopar”, “Vocasept”, “Ketanov”, “Gripeks Asset”, “Grippflu”, “Dolaren”, “ Kaffetin ”,“ Combigripp ”,“ Padevix ”,“ Spazgo ”,“ Paralin Extra ”,“ Hitflu ”.
Patient Reviews
Is Novalgin effective for menstruation? Reviews of the fairer sex report that this drug really eliminates all the pain associated with premenstrual syndrome. After applying one or two tablets, the woman's condition improves markedly (pulling pains in the lower abdomen and lower back go away).
It should also be noted that this medication effectively copes with other pain syndromes.