The medicine "Nurofen Express", the composition of which includes ibuprofen, belongs to the category of NSAIDs, derivatives of phenylpropionic acid. The product has anti-inflammatory, antipyretic and analgesic effects. The mechanism of influence of the drug is based on the ability to slow down the synthesis of prostaglandins due to the blocking of cyclooxygenase enzymes. From the digestive system, the drug is absorbed quickly enough. Communication with proteins occurs at 90%. The drug is slowly transported to the articular cavities, accumulates in the synovial tissue, and forms higher concentrations there than in plasma. The drug is metabolized in the liver. The active substance is excreted in the urine and in a small amount with bile.
The medicine "Nurofen Express." Instruction Indications
The medication is recommended for toothache, headache, rheumatic pain, migraine, algodismenorea. Indications include neuralgia, back pain, fever due to acute respiratory infections and flu.
The drug "Nurofen Express." Instruction Contraindications
It is not recommended for severe heart failure, severe arterial hypertension, lesions in the gastrointestinal tract of an erosive or ulcerative type in the acute stage. The drug "Nurofen Express" instruction does not allow for the appointment of leukopenia, "aspirin" bronchial asthma, urticaria caused by treatment with acetylsalicylic acid and other NSAIDs. Contraindications include hemorrhagic diathesis, a state of hypocoagulation, disorders in the activity of the kidneys or liver, pregnancy, lactation. The medication is not prescribed for hearing loss, in childhood (up to six years), with pathologies in the vestibular apparatus, as well as with intolerance to the components of the drug.
Dosage regimen
The drug "Nurofen Express" (tablets) is prescribed 200 mg to patients from the age of twelve three to four times a day. If necessary, get a quick clinical effect, the dose is increased to 400 mg three times a day. A day is not allowed to take more than 1200 mg. For children from 6 to 12 years of age, 200 mg are prescribed no more than four times. The drug is recommended for patients weighing more than twenty kilograms. Between taking the tablets, the interval should be at least six hours. Effervescent tablets are dissolved in a liquid (water), coated, swallowed whole and washed down.
The drug "Nurofen Express." Instruction Side effects
When taking the medicine for two to three days, negative phenomena are almost not observed. With prolonged therapy, there is a risk of nausea, hepatitis, constipation, pancreatitis, reversible optic neuritis. The drug can cause diplopia, flatulence, heartburn, discomfort in the epigastrium, increased pressure, tachycardia. In some patients, leukopenia, allergic rhinitis, shortness of breath, increased sweating may occur during treatment. A medication can sometimes also provoke cystitis, polyuria, nephrotic syndrome, anemia, agranulocytosis.