This remedy is a medicinal herbal product belonging to the group of antidepressants. Often used for the treatment of HC diseases. In the article, we consider the instructions for using Deprim.
Release form
The drug is produced by the manufacturer in two dosage forms - in the form of tablets and in the form of capsules. Deprim tablets are round, convex and green in color, coated. Packed in blisters of 10 pieces. Each cardboard box can hold from three to six blisters.
Capsules "Deprim" opaque, gelatinous, colored in green. Inside them are granules of brown or green, with a specific smell of St. John's wort. Capsules are packaged in blisters, like tablets, in 10 pieces. Each cardboard box can contain 2, 4, or 6 blisters. Reviews about "Deprim" are abundant. They will be described later.
Structure
St. John's wort extract was used as the main active ingredient in Deprim. Additional components in the tablets are lactose, colloidal silicon dioxide, magnesium stearate, talc, microcrystalline cellulose. The tablet shell consists of purified water, talc, carnauba wax, titanium dioxide, polyethylene glycol, blue glaze, green glaze, hydroxypropyl methylcellulose.
The drug in the pharmacological form of tablets includes 60 mg of dry hypericum extract. The use of tablets is unacceptable in the treatment of children under 6 years of age.
The capsules contain 425 mg of dry hypericum extract. It is forbidden to take them to children under 12 years old.
Instructions for use of the drug recommends taking it regularly, at about the same time. Treatment should be carried out under the close supervision of a physician.
Pregnant women may take the drug, but only if it is assumed that the benefit will exceed the potential harm to the fetus.
Analogs of "Deprim" consider below.
Pharmacological effects
Deprim tablets have antidepressant and anxiolytic effects. According to patient reviews, against the background of the action of the active component of the drug, the following therapeutic effects are observed:
- The patient’s sleep is normalized.
- The functional state of both the central nervous system and autonomic NS improves.
- The mood improves.
- Normalized psychological, as well as physical activity.
The pharmacological effectiveness of Deprim is due to the action of the components of St. John's wort extract - hyperforins, flavonoids, pseudo-hypercins.
Indications and contraindications
According to the instructions for use with "Deprim", the main conditions in which the drug is indicated are:
- Low mood.
- A mild to moderate form of depression.
- Anxious conditions, including those caused by menopausal changes.
- Increased susceptibility to weather conditions.
The drug should not be taken in patients with:
- Intolerance to any component that is part of the drug.
- Severe depression.
Before taking the drug, you need to familiarize yourself with the indications for "Deprim", as well as with contraindications.
Application
The drug is intended for oral administration. Drink it with a sufficient amount of liquid. The necessary dosage, form of release and duration of therapy should be determined by the doctor after a survey and examination of the patient.
Children from 6 years old should take up to 2 tablets once, for adults - 1 tablet three times a day. On average, the course of treatment takes 1 month.
Children from 12 years old are recommended a single or double intake of 1-2 capsules.
The optimal therapeutic effect is achieved after several weeks of regular administration of the medication.
If you miss the next dose, you should take the missed tablets as soon as possible. If at this moment the time has come for the next dose, then the dosage should be doubled to compensate for the missed dose. It is strictly forbidden to increase the dosage of the drug recommended by the doctor.
Side effects
According to reviews about Deprim, a variety of undesirable effects from the gastrointestinal tract and central nervous system may develop against the background of using the drug. The occurrence of allergic and dermatological reactions is not excluded.
There are reviews that patients from the use of the medication showed signs of nausea, developed vomiting, a feeling of tiredness and increased anxiety, and there was swelling and itching of the skin. If the patient has an increased sensitivity to sunlight, the risk of sunburn significantly increases. At risk are patients with fair skin.
Side effects of Deprim are described in detail in the instructions.
Overdose
With an overdose of Deprim tablets, a significant increase in side effects is observed. Patients may report general fatigue, drowsiness, and decreased performance.
If there are signs of an overdose, the drug should be discontinued, absorbent agents, for example, activated charcoal, should be taken. Further, it is recommended to consult a doctor to get recommendations for symptomatic overdose therapy.
Patients undergoing therapy using Deprim should refrain from staying in the sun and from visiting tanning salons throughout the duration of use of the medication, as well as within 14 days after completion of its administration. It is recommended to use closed clothing, special protective equipment and sunglasses.
Data on acute poisoning by St. John's wort is currently not available. However, there are rare reviews of the development of confusion and seizures in cases where the dosage of the active component has been exceeded to 4.5 mg for a long time.
Interaction with other medicines
What is the compatibility of Deprim with other drugs? Particular care is recommended to be taken when combining it with Indinavir, Roserpine, Cyclosporin, Theophylline, serotonin reuptake inhibitors, anticonvulsants, tricyclic antidepressants, tryptates, and oral contraceptives.
With the parallel use of Deprim with anesthesia and opioid analgesics, an increase in the therapeutic effect of these substances can be observed.
With simultaneous administration with St. John's wort extracts, the therapeutic effect of methadone, finasteride, simvastatin, benzodiazepine and all its derivatives is reduced.
Simultaneous use with photosensitizing agents increases the phototoxic effect.
"Deprim" is able to reduce the hypotensive effect of drugs containing reserpine.
Reception of "Deprim" while taking oral contraceptives reduces their effect, increases the risk of developing intermenstrual bleeding.
It is necessary to maintain the time interval between receptions of "Deprim" and drugs belonging to the group of MAO inhibitors. Between courses of therapy with these substances must pass at least 14 days.
If there is a need to take any medications, you should inform your doctor about taking this medication.
In addition, the medication negatively interacts with medications, which are based on the enzyme cytochrome P450.
Special instructions for taking the medication
It is important for patients to remember: if the therapeutic effect of taking "Deprim" does not occur within a month, you should abandon this medication and consult a doctor for advice.
During therapy, it is important for patients to refrain from drinking alcohol, since severe inhibition of the central nervous system functionality is not ruled out.
"Deprim" inherent pronounced sedative effect. Therefore, during therapy with this drug, it is recommended to refrain from driving a car and controlling complex mechanisms that require increased attention.
It is important to remember that the drug contains lactose, which, accordingly, indicates the impossibility of using the sedative “Deprim” in patients with glucose-galactose malabsorption syndrome and galactose intolerance.
Store the drug in a place that is protected from sunlight and inaccessible to children. Optimum storage at a temperature not exceeding 25 degrees Celsius.
You can buy the drug in almost any pharmacy, freely, a prescription from a doctor is not required.
The cost of "Deprim", analogues of the drug
The average cost of a medicine in Russian pharmacies depends on the pharmacy through which it is sold, as well as the region of sale. 20 capsules of the drug cost an average of 200 rubles, 30 tablets - 160 rubles.
The most common analogues of Deprim are: Life, Doppelgerts Nevrotonik, Negrustin, Gelarium Hypericum, Novoimanin, Mirtel, Venlift, Venlaxor, Prefaxin, Velaxin, Neuroplant, Alventa, Deprivit, Hyperflav, Melitor, Azafen, Incazan, Befol, Pipofezin.
If for one reason or another it is necessary to replace the drug with another one that is similar in composition or therapeutic effect, it is important to consult a doctor first for advice.
Reviews about "Deprim"
Reviews about the drug are mixed. Many patients resorted to self-treatment with Deprim before seeking medical attention. As a result of such neglect, the patient’s disease was aggravated, the doctor had to use more potent drugs. Therefore, doctors note that St. John's wort extract can be effective and will not cause an aggravation of the condition if its use is aimed at eliminating mild depression, mood swings, apathy.
However, positive reviews about the drug are also enough. Patients report that the medication is effective in combating seasonal mood swings, as well as after losing loved ones, during stressful periods of life. The effectiveness of the drug has been proven, but it occurs only with prolonged and systematic administration.
Negative side effects while taking Deprim are extremely rare. Often patients report that the drug is better tolerated if taken before bedtime, and not as indicated in the instructions in the morning or afternoon.
Separately, patients in reviews of "Deprim" note the fact that it is a phytopreparation and has an almost natural composition, respectively, the risk of adverse reactions is significantly reduced.
The effectiveness of the drug was also noted by women experiencing menopausal changes, while the use of the drug significantly improves the emotional state.
The next important positive side of the drug, which is often reported by patients, is its cost. "Deprim" is an effective drug at an affordable price.
Nevertheless, despite all the positive responses, it is important to remember that antidepressants, even of plant origin, should be prescribed exclusively by a doctor.