According to medical statistics, more and more people fall ill with depression each year. At the same time, this ailment has also become younger in recent years. Of course, many medications have been developed and are now available to treat depression. For example, if a person has a similar problem, the doctor may prescribe him “Profluzak”. In the instructions for use, it is recommended to use this drug for depression.
Release form and composition
Pharmaceutical companies release this medicine in the form of capsules. Profluzac is delivered to pharmacies in ordinary plates packed in cardboard boxes. This medicine is also available in tablet form. The main active ingredient of this drug in any case is fluoxetine.
How does it work
The antidepressant Profluzac is a selective serotonin reuptake inhibitor. Once in the patient’s body, he:
- reduces tension;
- eliminates feelings of anxiety and fear;
- removes dysphoria;
- improves mood.
Unlike many other antidepressants, Proflusac does not cause sedation or orthostatic hypotension.
Pharmacokinetics
Once in the patient's body, the active substance of this drug begins to be absorbed from the digestive tract into the blood. At the same time, the digestibility of Profluzak can reach up to 95%. Eating can slow down the absorption of fluxetin. The maximum concentration of the active substance of the drug in the patient's blood plasma reaches 6-8 hours after administration.
A feature of Profluzak is that it accumulates well in tissues. Also, the active substance of this drug easily penetrates the blood-brain barrier.
The drug is metabolized in the liver. At the same time, it is excreted from the body with urine and partially with feces. With any diseases of the kidneys, the rate of removal of Profluzak from the tissues does not decrease. Unfortunately, this medicine can pass freely into breast milk.
Indications
According to the instructions for use, Profluzac is supposed to be taken with depression. Moreover, he can be prescribed for any form of such a disease - mild, moderate, severe. Also, this medicine may be prescribed by doctors when:
- bulimia;
- alcoholism;
- anorexia;
- obsessive states.
The instruction to "Profluzak": dosages
The doctor develops a treatment regimen with this tool, depending on the specific type of disease and the patient's condition at a given time. In depression, the initial dose in most cases is 20 mg / s. Doctors recommend taking medicine once a day - in the morning. In the future, the dose, if necessary, is increased by another 20 mg.
In any case, more than 80 mg of Profluzak per day should not be taken. Moreover, this amount of medicine is supposed to be divided into 2-3 doses.
Depression, as you know, very often affects the elderly. For such patients, the drug in most cases is prescribed in the amount of 60 mg in 3 divided doses. In obsessive conditions, the dose may be equal to 20-60 mg / day. In bulimia, the drug is usually prescribed in a dosage of 60 mg / day in 2-3 doses.
Sometimes "Profluzak" can be used by doctors and as a means of maintenance therapy. In this case, the drug is usually used at a dosage of 20 mg / day.
Persistent clinical effect of taking the drug occurs in patients no earlier than after 1-2 weeks of treatment. But most often, the course of treatment with Profluzac lasts 3-4 weeks.
Are there any contraindications
The description of Profluzac given above allows us to judge it as a drug that is quite effective. But like any other antidepressant, Profluzac can be prescribed, of course, by no means to all patients. Contraindications to the use of this drug are:
- severe liver failure;
- pregnancy;
- lactation period.
In no case should this drug be prescribed to patients with suicidal tendencies. This medicine has been seen to increase suicidal tendency.
Also, you can not take this tool simultaneously with MAO inhibitors. Do not prescribe Profluzak, even if the patient took such drugs two weeks before starting treatment for depression. MAO inhibitors themselves are only allowed to prescribe to patients 5 weeks after the end of the Profluzac treatment course.
In which cases it is prescribed with caution
Sometimes it happens that the patient has no particular contraindications to taking Profluzak, but he should drink this remedy under the special supervision of a doctor. With caution, this drug is prescribed to people with the following health problems:
- diabetes;
- Parkinson's disease;
- compensated liver failure;
- cachexia.
Also, with great care, you need to drink this drug for people suffering from renal failure.
What side effects can cause
In many cases, when taking this antidepressant, a negative reaction of the body also appears in patients. The main side effects of Profluzak in patients from the nervous system are:
- hypomania or mania;
- increased suicidal tendencies;
- headache;
- tripod;
- tremor;
- dizziness;
- asthenia;
- sleep disturbances.
This medicine can negatively affect the patient's digestive tract. In this case, the patient may experience the following symptoms:
- nausea;
- decreased appetite;
- dry mouth
- diarrhea;
- increased salivation.
Some patients are allergic to Profluzak. This is manifested primarily by urticaria and itching. Also, when taking this antidepressant, the patient may experience the following side effects:
- weight loss;
- decreased libido;
- systemic disorders of the kidneys, liver and lungs;
- vasculitis;
- increased sweating.
special instructions
As already mentioned, Profluzak, among other things, can provoke a strong decrease in the patient’s body weight. Therefore, very thin people should prescribe it with caution. In patients with diabetes, this medicine increases the risk of developing hypoglycemia. Such patients should be under the supervision of a doctor for some time after drug withdrawal. During this period, they may develop hyperglycemia with a high degree of probability. In any case, the dose of insulin in the treatment of Profluzac is adjusted for patients.
What will happen with an overdose
The instructions for use with Profluzak, as well as the doctor’s recommendations when treating them, must be observed. Take this drug more than prescribed by the doctor, of course, it is impossible. An overdose of the drug can be very dangerous. The patient in this case has the following symptoms:
- convulsive seizures;
- motor anxiety;
- heart rhythm disturbance;
- tachycardia;
- nausea and vomiting.
Patients also need to be careful in the use of Profluzak because pharmacists have not yet found antagonists for this drug. Treatment for overdoses of the drug is symptomatic. That is, the stomach is washed to the victim, and then give activated charcoal or some other sorbent.
Interaction
Drinking Profluzac in combination with MAO preparations, as already mentioned, is by no means possible. Doctors do not prescribe this medicine at the same time, for example, with Prokarbazip, Furazolidone, Selegilin, Tryptophan. Combined therapy with such means leads to the development of a strong sedative effect in the patient, manifested:
- confusion of consciousness;
- motor anxiety;
- cramps
- agitation;
- dearthritis;
- chills and tremors;
- hypertensive crisis;
- diarrhea, etc.
According to the instructions "Profluzak" in no case should not be taken simultaneously with alcohol. This can lead to intoxication of the body. In addition, the active substance of this drug is able to enhance the effect of alcohol.
Carefully take "Profluzac". The instructions for use recommend along with such means as:
- hypoglycemic drugs;
- central action drugs that cause CNS depression.
"Fluxetin" is able to enhance the effect of these drugs. Also, Profluzak is able to block:
- Tetracyclic and tricyclic antidepressants.
- "Carbamazepine."
- "Metoprolol."
- Trazadon.
- Cherfenadin.
- Diazepam and some others.
Along with such drugs, this medicine is usually not prescribed.
Analogues of the drug
The cheapest synonym for Profluzac is Fluoxetine. Also, instead of this drug, doctors can prescribe to patients:
- "Thorin" (the active substance is sertraline).
- "Citalopram."
The last drug is more expensive than Profluzak. This analogue can be prescribed including for panic disorders. By contraindications, it is slightly different from Profluzak. In any case, you cannot change this drug to it yourself, without consulting a doctor. This can lead to sad consequences.
Reviews about Proflazak
According to patients, this drug is really very good at raising mood in depression. The advantages of this tool, many netizens include the fact that after taking it, your appetite disappears. Some people even drink Proflazac for weight loss. However, for this purpose, of course, it is not intended. Most patients are still advised to drink this medicine as directed. Many network users recommend taking this drug for two weeks in any difficult life situations.
Appetite, this medicine reduces, according to patients, very much. There are good reviews from those who have lost weight about Proflouzak. However, you should not risk your health when taking this drug with the goal of losing weight. Judging by the reviews, he can give "side effects" very serious.
In general, Profluzac patients are praised. However, this medicine is not suitable for all patients. It does not help some people at all, while for others it causes many side effects. Also, some consumers note that “empty” batches of this drug are often found on sale at the moment. Drinking such a Proflouzak, of course, will be completely useless.
Storage
Many patients are interested in including whether Profluzac is sold by prescription or not. Previously, this effective medicine could be purchased at a pharmacy just like that. However, subsequently they began to sell it only with a prescription. Today, this product cannot be found on free sale. This is also why people who want to lose weight are better off looking for another means specifically designed for this purpose.
Buy "Profluzak" without a prescription is almost impossible. Acquired on the recommendation of a doctor, the drug, among other things, must also be properly stored. Like most other medicines, keep Profluzac in the house in a cool, dry place. Store this drug at temperatures up to 25 ° C. Of course, this medicine should be kept in a place where children or, for example, pets cannot reach it. The shelf life of the drug is 2.5 years from the date of issue.
It is important to remember that depression is not just a whim. This is a serious disease requiring compulsory treatment. Moreover, only a qualified specialist should conduct therapy. Do not self-medicate, including with the help of the drug "Profluzak", in no case.