In the article, we will consider the instructions for use, reviews and analogues to the drug "Poludan".
This is an antiviral drug based on a polyribonucleotide complex obtained by biosynthesis. The drug is intended for the treatment of herpetic and adenoviral infectious eye diseases. It has antiviral and immunomodulatory effects.
The principle of its "work" is associated with the excitation of the synthesis of endogenous interferons and cytokines in the blood and interferon in the lacrimal fluid.
So, what does the instruction to the “Midday” tell us?
Release form and composition of the drug
“Poludan” is available in the form of a lyophilisate for the preparation of injections. One bottle contains a complex of polyadenylic and polyurelic acid, potassium salts of polyribodenyl and polyriburedyl acids, as well as excipients, which are potassium and sodium dihydrogen phosphates, sodium chloride.
The mechanism of action of the drug
According to the instructions, “Poludan” stimulates the production of endogenous interferons and cytokines by the immune system and increases the activity of natural T-killers, which determines the production of gamma-interferon and recognition of foreign antigens.
Daily administration of the drug allows you to maintain a high level of interferon throughout the course of treatment.
Indications for the use of a medication
In what cases is the drug prescribed? As indicated by the instructions for use, drops of "Poludan" are used to treat such superficial viral infections of the eyes as herpetic and adenovirus, including the following:
- conjunctivitis;
- keratoconjunctivitis;
- uveitis;
- choreoretinitis;
- iridocyclitis;
- keratitis;
- deep keratitis;
- keratouveitis.
Dosage and administration
According to the instructions for "Half-Dan", the solution is prepared by dissolving the contents of the vial in 1 ml of water for injection or novocaine.
The prepared solution is instilled in two drops in a cavity between the posterior surface of the eyelids and the anterior surface of the eyeball itself in the affected eye. In no case should you bury the drug directly on the eyeball.
In case of exacerbation, it is necessary to treat the eye up to 8 times a day, as the condition improves, the number of treatments decreases to 3-4 per day. The duration of the course of treatment is determined by the attending physician and is usually 7-10 days.
This is also confirmed by the instruction for drops of "Middan".
The drug is harmless to children, and therefore can be used in pediatrics. However, consultation and observation by a specialist is necessary, which will determine the dosage of the drug and the duration of the course of treatment.
Drops are often prescribed in conjunction with injections of the same drug. With subconjunctival injections, it is sufficient to use it once a day.
If the patient wears contact lenses, then they are removed before the procedure, and put on 20 minutes after it.
Compatibility with other medicines
According to the instructions to “Poludan”, it can be used together with other drugs intended for the treatment of viral infections and antibiotics, since this does not reduce the effectiveness of the treatment as a whole.
However, it is undesirable to use it in conjunction with enzyme medicines, since such a combination reduces the therapeutic effect of "Middan".
In what cases can it be unsafe?
Contraindications
As indicated by the instructions for use for "Half-Dan", eye drops have no contraindications for use. An exception is the individual intolerance of any main or auxiliary component of the drug.
The use of the drug during pregnancy
Currently, there is no data on the use of the drug during pregnancy or lactation. However, according to most doctors, the drug does not adversely affect the development of the fetus or the health status of the newborn.
Nevertheless, before using the drug during pregnancy, a doctor’s consultation is recommended. Only a specialist will be able to objectively assess the possible risks, prescribe an adequate, safe treatment, choose the right dosage and duration of the course.
Side effect of the drug
The use of eye drops can lead to such unpleasant consequences as local allergic reactions or severe irritation of the eyes, manifested in the form of itching, burning, redness. As a rule, side effects do not require special treatment and disappear on the first or third day after stopping the use of the drug.
Overdose of medication
Currently, no cases of overdose with this drug have been recorded.
Alcohol compatibility
Like any antiviral agent, this drug is undesirable to use simultaneously with alcohol. Alcohol reduces the therapeutic effect of the use of the drug, enhances the manifestations of side effects.
About this warns the instruction to the "Half-Dan" for the eyes.
Analogs of this medication
There are similar medications. These include:
- Okoferon is an antiviral agent with a similar effect, but a completely different composition.
- "Oftaloferon", which has a similar antiviral effect, but differs in composition and does not cause side effects.
- "Actipol" is an antiviral and immunomodulatory drug, which includes aminobisoy acid.
Reviews of ophthalmologists
Most ophthalmologists widely use in their practice drops of “Middan”. Experts note that the drug practically does not cause adverse reactions and is a very effective tool in the spread of colds, which are often complicated by viral infections of the eyes.
Patient reviews about the drug
Patients' opinions about the drug are mixed: there are both positive and extremely negative reviews.
Many patients who have used Poludan for the treatment of conjunctivitis, keratitis and other viral diseases of the eyes note that a positive effect becomes noticeable only a couple of hours after the first application: itching and burning disappear, lacrimation and purulent discharge stop or noticeably decrease. Some patients noted that the effect of the drug occurs immediately, before the first noticeable improvements appear, several days pass.
There are negative reviews about the drug. Most often, dissatisfaction is caused by the short shelf life of the finished product, inconvenient packaging, the need to buy additional water for injection and independently prepare a medicinal solution. Occasionally, patients note the appearance of pronounced adverse reactions, which, however, pass within a couple of days after the completion of the course.
Rarely observed drug inefficiency. However, most often this is due to an initially incorrect diagnosis or the use of the drug without consulting an ophthalmologist. This tool is suitable only for the treatment of viral infections and is not effective in the case of the bacterial nature of the disease.
We have reviewed the instructions for use for the drug "Poludan".
conclusions
Eye drops "Poludan" - an ophthalmic agent for combating viral infections of the eyes of herpetic and adenovirus nature. The drug has an antiviral and immunomodulating agent. The drug is dispensed from pharmacies exclusively by prescription.
This tool is perfect for complex therapy, as it interacts well with other antiviral drugs. Once again, we emphasize that “Poludan” is not suitable for use simultaneously with enzyme medicines, which reduce its therapeutic effect. Also, do not combine the drug with alcoholic beverages. However, this rule is common to all antiviral drugs.
The advantages of the tool include its high effectiveness in the treatment of viral infections, low cost, the ability to use it yourself. In addition, there are practically no contraindications to use.
Among the shortcomings, it should be noted the need to buy water for injection in addition to the drug and independently prepare a solution. Moreover, dispensing from pharmacies is carried out only by prescription, it has many side effects (eye irritation, allergic reactions, edema).