“Thiamine chloride” is a synthetic preparation of vitamin B1, which refers to water-soluble vitamins and is converted into cocarboxylase in the body. And already it is a coenzyme of enzymatic reactions. The specified vitamin is actively involved in protein, as well as fat and carbohydrate metabolism.
Thiamine chloride is taken parenterally, so it quickly enters the bloodstream and is subsequently distributed between tissues and organs. The phosphorylation process occurs in the liver, after which it accumulates in the heart, liver, kidneys, brain, spleen. About 10% of this vitamin is excreted from the patient’s body through the kidneys and liver.
Indications for the use of this tool
“Thiamine chloride” is a vitamin, and it is prescribed in the presence of vitamin deficiency or hypovitaminosis B1, as well as for the treatment of radiculitis, encephalopathy, neuritis, peptic ulcer, neurasthenia, peripheral paralysis, polyneuritis, peptic ulcer of the duodenum. It is also prescribed in the presence of liver diseases, peripheral vascular spasms, eczema, dermatosis of neurogenic origin, myocardial dystrophy, intestinal atony, neuralgia, psoriasis, pyoderma and itching of the skin.
"Thiamine chloride" - instructions for use
A 5% solution of this drug for adults and for children is administered 1 time throughout the day, the procedure is carried out daily. For children, the daily dose is not more than 0.25 ml, and for adults, 1 ml of this solution. Typically, the course of treatment with the drug is from 10 to 30 injections.
Possible side effects
The use of Thiamine Chloride can cause allergic reactions, and sometimes anaphylactic shock. The most prone to their occurrence are patients who are prone to allergies, and have allergic reactions to B vitamins in history.
Contraindications
The drug can not be taken with hypersensitivity, hypertension, as well as in the presence of allergic diseases and idiosyncrasy. Caution should be taken "Thiamine chloride" for people who have increased excitability of the nervous system and hyperacid forms of duodenal ulcer.
Do not allow mixing of the specified drug with solutions that include sulfites. This leads to the fact that "Thiamine chloride" in them completely decomposes. It is also not recommended to take this vitamin with vitamins B6 and B12.
Overdose
If this drug is taken in high doses and for a fairly long period of time, then symptoms such as headache, tremor, agitation, insomnia, and increased heart rate may develop . Usually, after discontinuation of this drug, all these symptoms disappear themselves, but if necessary, symptomatic treatment should be carried out.
Injections are carried out to obtain a faster result, as well as patients who have impaired bowel function. But it is recommended to start with small doses of the drug, they should not exceed 0.5 ml of a 5 percent solution, if the drug is well tolerated, then its dose is adjusted to the recommended amount. If the drug is administered intravenously, then this must be done very slowly, and if into the muscle, then deeply. During injections, minor painful sensations can sometimes occur, which is explained by the low pH of the solution. Alcoholics and women who are in menopause and premenopausal periods may experience increased side effects.
It is not recommended to mix “Thiamine chloride” in the same syringe with streptomycin or penicillin, since the antibiotic is destroyed, and also mix it with nicotinic acid, since thiamine is destroyed.