The human body is so subtle and at the same time complex device that even the smallest disturbances can lead to serious consequences, especially if they relate to hormonal balance. Unfortunately, such changes can lead both to a number of diseases and to such a terrible diagnosis as infertility, which more and more women have recently heard about them. And even 30 years ago, with a hormonal imbalance, this sentence was heard by a huge number of women without hope of recovery, now doctors are using the drug “Dufaston” to try to influence the state of the body, and, as statistics show, such treatment helps many. The action of this drug is aimed at combating progesterone deficiency. This is a fairly common cause of reproductive dysfunction, which is faced by a huge number of girls who want to become a mother. This is a serious, but solvable problem, about which there is now a lot of discussion among both doctors and patients.
How to apply and for what Duphaston
Nowadays, almost every woman who is faced with the problem of lack of pregnancy is prescribed hormone therapy. As a rule, progesterone-containing drugs are used for this. Why “Dufaston”, if the cycle is not broken and outwardly it seems that everything is in order? This is the question most often asked by doctors a huge number of girls to whom he is appointed. The fact is that the regularity of the cycle can in no way be a guarantee of pregnancy. For its onset, ovulation is also necessary, which without a certain amount of the female hormone progesterone in the body is simply impossible. In addition, thanks to this drug, a favorable environment is formed in the uterus for fixing the fertilized egg.
Also often asked the question "Why Dufaston?" women suffering from various gynecological diseases. The answer to it can be found in the cause of these ailments. As a rule, this is the same imbalance of the hormonal background with a pronounced lack of progesterone.
Reception "Duphaston" can only appoint a doctor after a certain series of laboratory tests. The dose in each case is different, however, the manufacturers of this medication in the instructions indicated the recommended dosage regimen:
- with endometriosis, 10 mg of the drug should be taken from the fifth to twenty-fifth day of the cycle 2-3 times a day;
- to reduce premenstrual syndrome, the drug is prescribed 10 mg twice a day from the eleventh to twenty-fifth day of the cycle;
- To stop bleeding, Duphaston tablets are taken together with estrogens of 10 mg for 5-7 days;
- with dysmenorrhea, it is recommended to use 10 mg of the drug from the fifth to the twenty-fifth day of the cycle;
- to eliminate amenorrhea, complex hormone therapy is prescribed, which also includes 10 mg of progesterone;
- in case of infertility, the Duphaston medicine is used to get pregnant using 10 mg from the fourteenth to twenty-fifth days of the menstrual cycle for 3-6 months, and when pregnancy occurs, up to 20 weeks to exclude self-abortion.
- with the threat of spontaneous abortion, the drug is used 40 mg once, and after 10 mg every 8 hours, strictly observing the time interval between doses to maintain a constant level of progesterone in the body;
- to normalize menstruation, the drug "Dufaston" is also prescribed 10 mg in the period from 11 to 25 days of the cycle.
The composition of the drug "Duphaston"
The drug is a film-coated tablet, which contains 10 mg of the active substance dydrogesterone, which is an analogue of the real female hormone progesterone. The following substances were used as auxiliary components: lactose, starch, gelatin, magnesium stearate and talc. This composition of the drug is very effective, when used internally, it ensures the correct development of the endometrium and neutralizes the action of the male hormone estrogen, the excess of which negatively affects the female body. When used correctly, the drug eliminates the deficiency of female sex hormones and thereby normalizes the functioning of the female reproductive system, including reproductive function.
The drug "Duphaston" - side effects and warnings
Duphaston tablets, like any other chemical preparation, have a number of warnings and contraindications, which are clearly indicated by the manufacturer in the instructions for the drug. One of the first to highlight the intolerance of the components. If you ignore it, taking the medication can provoke allergic reactions, ranging from a simple rash of hives and ending with a more severe form, such as anaphylactic shock. It is also strictly forbidden to take the drug by people with Dubin-Johnson and Rotor syndromes.
Along with prohibitions, the instructions also describe precautions for admission. So, for example, bleeding may occur during therapy, which is eliminated by increasing the dose of the drug. Particular attention should be paid to the patient’s medical research before prescribing treatment, this is due to the fact that Dufaston is a hormonal drug, and its excess can adversely affect the functioning of the reproductive system.
The special instructions say that this drug can be used during pregnancy, but with lactation its use is extremely undesirable, since the hormone penetrates into breast milk, and this is completely useless for the baby.
Therapy with Duphaston medication does not affect the ability to drive a car or work in production with a high degree of danger.
Among the side effects, the following conditions are noted:
- from the circulatory system, in rare cases, hemolytic anemia was observed;
- hypersensitivity with severe skin rashes, and in rare cases, Quincke's edema;
- migraines and headaches;
- breast sensitivity and rare bleeding, eliminated by an increase in dose;
- minor disturbances in the liver, jaundice and abdominal pain.
However, such manifestations occur in isolated cases and often the drug "Dufaston", whose side effects depend on the state of the body as a whole, is well tolerated.
The drug "Duphaston" and pregnancy
A fairly frequent cause of infertility and early termination of pregnancy in girls is the lack of female hormone in the body. That is why doctors prescribe a synthetic female hormone, which is included in the drug "Dufaston", when planning pregnancy. The active substance of this drug in structure is very close to the natural hormone and, getting into the female body, completely replaces it. But why "Duphaston" and how is it associated with the onset of pregnancy? To answer these questions, you need to understand a little how the woman’s reproductive system works and what role progesterone plays in it. This female hormone is produced by the ovaries and, together with an equally important estrogen, it forms the mucous membrane in the uterus, in which certain changes occur throughout the entire monthly cycle. In the initial period of the cycle, when menstruation is taking place, progesterone in the blood is not as pronounced as estrogen, due to which there is a multiplication and growth of the cells lining the uterus. On a certain day, ovulation occurs, as a result of which the egg leaves its ovary, in which it developed, and the so-called corpus luteum forms in the place of its follicle . It also produces such important progesterone. A rapid change in the concentration of this hormone affects the lining of the uterus, making it loose. At the same time, cell growth decreases, and a mass of blood vessels appears in the structure of the internal cavity. Such changes are very important so that in the event of fertilization the egg can gain a foothold and subsequently receive the necessary nutrition.
Knowing what changes occur in the female body in each specific segment of the monthly cycle, it is difficult to underestimate the importance of the level of concentration of progesterone in the blood. And if its growth does not occur naturally, they use the drug "Dufaston" for this, pregnancy with which occurs much faster.
This drug is prescribed not only when planning pregnancy. It is used to preserve it. This is due to the fact that progesterone creates a favorable environment in the uterus for the life of the embryo, and the dose at this stage of therapy is often increased. For those who take this medication during pregnancy, you need to know not only about changes in the uterine mucosa. It should be noted that the drug affects the muscles of the uterus, relaxing it and removing tone, and prepares the mammary glands for lactation.
It should be noted that Dufaston is used not only when pregnancy has occurred with its help. It is prescribed for those women who, being healthy, became pregnant on their own, but for some reason have the risk of miscarriage in the early stages.
Reception of the drug "Dyufaston" with hormonal disorders
Quite often, those women who need a malfunction for one reason or another need the hormonal therapy. The consequences of such violations can be very different. The most common problem is an irregular cycle with a partial or complete absence of menstruation or a tumor in the ovary such as a cyst. "Dufaston" as a hormonal surge in this case is simply necessary.
Often a cyst forms in the corpus luteum and resolves independently with a natural increase in the level of female hormone, however, if the desired concentration of progesterone is not achieved, it continues to increase. In this case, drug therapy is not just desirable, but required.
Quite often, this drug is prescribed for delays that are not a sign of pregnancy. In this case, it is prescribed along with the course of the so-called female vitamins, including vitamin E in oil and folic acid. If you see a doctor on time and start taking Dufaston tablets, the delay will not be long and the next menstruation will come on time.
Is Duphaston needed
Each woman decides for herself whether to use synthetic hormones or to hope that the process of increasing progesterone in the blood will recover itself. The reason for such failures may lie not only in some pathologies of the reproductive system, but also in stressful situations or nervous and emotional stresses. Such violations, as a rule, pass by themselves as soon as the psychoemotional state is restored. To normalize the hormonal background in these cases, sedatives and a course of vitamins are prescribed.
How to stop taking the drug "Duphaston"
In no case should hormone therapy be started without prescribing and observing the attending physician. Every woman must know this truth. After all, the independent use of such medicines negatively affects the health of any person. But not only the appointment should begin with a doctor’s recommendation, the cancellation also cannot be abrupt, especially if pregnancy has occurred under the influence of Dufaston. Stop taking these pills, under the supervision of a doctor according to a certain scheme, especially if progesterone deficiency has been established by analysis. As a rule, they act like this: every few days they reduce the applied dose, first by a third, and then by half, gradually going to the minimum and refusing the drug at all. The harmless cancellation of Duphaston should last at least two weeks. Such actions are carried out both at the end of the treatment of gynecological diseases, and at the end of the medication during pregnancy. Usually, to preserve the fetus, the drug Dufaston is taken for up to 12 weeks, after which the dose is gradually reduced to nothing. It is believed that in this period, spontaneous abortion can happen only if there are several serious factors on which progesterone has no effect.
Reviews of doctors about the drug "Duphaston"
Almost all gynecologists and obstetricians in their practice resort to the use of hormone therapy with the Dufaston drug. Reviews about this drug are numerous and positive from both experienced doctors and beginners. The only thing that experts say is that the effectiveness of this therapy will depend not only on the individual characteristics of the body, but also on the correct diagnosis. For this, each patient should undergo a full examination, excluding all possible diseases caused by the infection, pass all kinds of smears and, of course, a blood test for hormones that will show the level of progesterone and identify possible problems associated with its concentration. It is worth considering that such an analysis is given on certain days of the cycle, when its growth is in the active phase.
It should also be noted that the regimen for taking these pills is important. How to drink Duphaston, only a doctor can tell, who will not only decipher the test results, but will also examine the patient personally. Only after seeing the big picture, the specialist will be able to give recommendations that will give a positive result.
Reviews of patients about the drug "Duphaston"
A huge number of women resorting to taking this drug, note its effectiveness. Some note that the use of the drug during menstruation delays caused the desired process after a week of administration. Others suggest that such therapy has had a positive effect on the diagnosis of infertility. And almost every second pregnant woman says that in the first trimester the doctor prescribed this drug in case of a miscarriage. Such patient reviews make a good advertisement for this tool. And although the drug is a chemical composition, it perfectly replaces natural progesterone, practically without causing any negative effects on the body. In addition, Dyufaston, whose price for most women, although not small, is affordable, is a new generation drug that does not increase weight, does not increase hair growth and does not change the tone of voice, as when taking gestagens of past years. And if earlier the word “hormone therapy” caused a violent reaction related to the consequences of such treatment, now most women who need such measures, without hesitation, agree to such treatment.
"Pros and cons"
First of all, in favor of taking this medicine, the Dufaston medication, the price of which varies between 550 rubles depending on the distributor, is a publicly available drug. Which is very important for the majority of the population, who are unable to lay out huge funds for artificial insemination with a diagnosis of infertility. The action of the drug is aimed at restoring the hormonal background of the female body, and it copes well with its task, regardless of whether it is a disease or threats of self-abortion. Reviews about this medication are mostly positive, so it can be considered verified in business. In addition, as the same practice shows, the drug is well tolerated and does not cause any physical changes and pain. This is one of the few hormone-containing drugs that has a minimum of contraindications and side effects.
The drawbacks in such therapy are at least, unless, of course, the fact that the drug is not natural, but chemical. However, often with a progesterone deficiency, such a remedy cannot be dispensed with, because, as a rule, the pathologies that caused such a dysfunction of the reproductive system themselves are not eliminated. For treatment, hormone therapy is needed.
The most important “contra” in this case is that treatment with this drug does not give a 100% guarantee of recovery or pregnancy, but, as an alternative treatment, along with many other therapies, it is quite appropriate. Therefore, no matter what the doctor recommends, only a woman can make the final decision on such treatment, having weighed all the pros and cons for herself, after reading the reviews and full information about this drug and its effect on the body.