In recent years, the tool "Momat Rino Advance" has become increasingly popular. It belongs to the class of glucocorticosteroids and is designed specifically for topical application. Available in several forms. You can buy a spray or drops. Momat Rino Advance is suitable for children and adults, has a minimum of contraindications, and the price is quite reasonable, about 200 rubles per package. Does this wonderful drug have any weaknesses? Who can and cannot use Momat Rino Advance? Read more about this.
What is this about?
"Momat Rino Advance" in the nose is available in the form of a spray. Inside the compact and easy-to-use bottle is a thick substance. It can be completely opaque or half transparent. Hue - white or close to it. One package is designed for 60 or 120 uses, depending on the volume. The instruction āMomat Rino Advanceā, placed on the package, contains a reference to how many times it will be possible to use a bottle enclosed in a cardboard box.
The bottle itself is made of plastic, it is necessarily equipped with a special device for dosed distribution. One cardboard box contains only one medicine package.
What is made of?
Describes what the spray "Momat Rino Advance" consists of, instructions for its use. It is indicated here that the main effect is provided by the active substance, namely, mometasone furoate monohydrate. When used in accordance with the rules for one application, the patient receives 50 Ī¼g of this compound.
To improve the effect of using the Momat Rino Advance spray, additional substances have been added to the composition. Among them - cellulose and carmellose represented by single crystals, which form the RC-591 Avicel, as well as a number of chemicals that enhance the effectiveness of the product and simplify its use. An important component is water, which is necessary for injecting the active ingredient onto the mucosa.
Features of pharmacological action
The main component specified in the instructions for āMomat Rino Advanceā is mometasone furoate. This compound is fully synthetic and belongs to the class of glucocorticosteroids. It is intended to combat inflammatory processes, as well as eliminate the effects of allergies. The product is designed for local use. A positive effect is achieved if the spray āMomat Rino Advanceā (instructions for use with the spray is always included) is consumed in a volume that does not lead to the development of a systemic effect.
Due to the presence of mometasone in the substance sprayed onto the nasal mucosa, the generation of lipomodulin, which interacts with phospholipase A, is increased in the body. This leads to a lower correction of the concentration of arachidonic acid. The next element in the chain of influence is a reduction in the production of prostaglandins, cyclic endoperoxides, which normally appear in the body as by-products of the processing of arachidonic acid.
What does this lead to?
Such an effect of spray, drops of āMomat Rino Advanceā allows to exclude regional accumulation of neutrophils. This positively affects the amount of inflammatory exudate (volumes are reduced). At the same time, the compounds produced by lymphokines also become smaller in volume. Macrophages stop actively migrating. Granulation, infiltration are slowed down and deactivated.
Reviews of āMomat Rino Advanceā indicate that the proper use of the product can prevent and stop an allergic reaction. This is due to the inhibition of the process of generating products obtained from the metabolism of arachidonic acid. In addition, the positive effect is due to a decrease in the concentration of free mediators, the source of which could be mast cells. If the inflammatory process has begun, under the influence of āMomat Rino Advanceā used in accordance with the instructions for use, it weakens. This is due to inhibition of chemotaxis generation processes. The drug acts on late allergic reactions, alleviating the human condition.
Medication in the body: what is happening?
It is important to use the Momat Rino Advance spray according to the instructions for use. The accompanying documentation indicates that the bioavailability of the active component in the human body when used āin the noseā does not exceed 1%. To clarify this indicator, a method was used whose sensitivity is 0.25 pg / ml. This describes the systemic availability of a substance.
When studying the effect of the drug on the gastrointestinal tract, it was found that absorption practically does not occur, only a small amount of the suspension can enter the body after inhalation of the substance in the nose. All this volume is processed quite actively, and this happens before excretion with fluids excreted from the body (urine, bile).
When can i apply?
Reviews about āMomat Rino Advanceā are positive if the product was used strictly for its intended purpose. Doctors recommend resorting to this drug if:
- polyps in the nose, leading to respiratory failure, loss of smell (recommended only for adults);
- acute rhinosinusitis (for ages 12 years and older), accompanied by moderate, mild symptoms, in the absence of severe infection by bacteria;
- acute sinusitis at the age of 12 years and older;
- chronic sinusitis at the age of 12 years and older, if an exacerbation has begun.
Reviews, instructions for use "Momat Rino Advance" note that the effectiveness of the medication remains when used at any age (over 12 years). The drug can be used in elderly patients. It is recommended to use the drug for adjunctive therapy for sinusitis, when the doctor prescribed a course of antibiotics as the main treatment method.
When else will it help?
The instruction for āMomat Rino Advanceā also contains references to the effectiveness of the drug in the allergic form of rhinitis. It can be used both with seasonal āattackā of the disease, and all year round. For allergies, the drug can be used from the age of two. There is no upper age limit, as follows from the instructions for āMomat Rino Advanceā.
The medication is considered an effective preventive measure when the allergy season approaches. If allergic reactions are characteristic in a severe and moderate form, and the patient has already reached the age of 12 years, then the drug begins to be used regularly half a month or a month before the expected start of the allergy-causing season.
And when not?
All contraindications are listed in the instructions for āMomat Rino Advanceā. First of all, it is necessary to note the injuries sustained recently. If the nasal mucosa has been damaged, spray is not allowed. Similarly, the restriction applies to those who have recently undergone surgery. It spreads until the wound is completely healed. In addition, usage restrictions are as follows:
- individual intolerance;
- hypersensitivity to any component of the drug.
Children's age does not impose an absolute ban, but creates certain restrictions: from two to 12 years old, the spray can be used only for rhinitis of an allergic nature. If polyps are detected, Momat Rino Advance is used only by adult patients. You can treat sinusitis with this remedy when you reach 12 years of age.
We use, but carefully
In some cases, as indicated in the instructions for the drug, it is necessary to use Momat Rino Advance very carefully, with regular monitoring of the patient's condition. The choice in favor of this spray is made if the indications are strict, but alternative medicines were ineffective or not applicable to a greater extent than Momat Rino Advance. The doctor must evaluate the possible risks of such therapy and notify the patient about this, only after that they begin treatment.
The list of situations that force the use of the nasal spray āMomat Rino Advanceā is strictly neat:
- active local infectious tissue damage affecting the nasal mucosa;
- tuberculosis of the respiratory tract (the use of the drug in both latent and active forms will be equally dangerous);
- systemic infection with a flexible, virus, bacteria;
- Herpes simplex infection, accompanied by affected areas.
How to use correctly?
You can read about how to correctly apply the spray, drops of Momat Rino Advance in the instructions. The medication is intended for intranasal use. The packaging is not only a plastic bottle with an active substance, but also a special dispenser that simplifies proper use.
Before applying the spray for the first time, you need to calibrate the bottle. To make it simple, just click on the nozzle to dispense the substance 10 times. By the tenth press, splashes will appear. As soon as the remedy begins to arrive, the bottle is ready for use. If the use of the medication is irregular and more than two weeks have passed since the last time, before reuse it is necessary to first press the bottle dispenser twice test, making sure that the spray appears in normal volume.
Practical application: it can never be easier
Before introducing āMomat Rino Advanceā onto the nasal mucosa, the head is tilted. Then, a medication is injected into each nasal entrance. As a rule, the doctor, when prescribing the medicine, gives recommendations on injection, in particular, on the number of doses. Usually spray once or twice in the nasal passage, this has a sufficient effect on an adult.
From time to time, the dosing unit must be cleaned to ensure proper operation and the correct amount of suspension. The process is quite simple. First remove the protective cap, then remove the tip. These parts are washed under running warm water, rinsed, gently dried, all the while monitoring the ambient temperature (it is forbidden to expose to frost or direct sunlight in summer). Dry and clean parts are secured in the reverse order on the bottle: first the tip, then the dispensing aerosol.
We follow the rules
The manufacturer draws attention to the fact that piercing the applicator and opening the vial with the use of sharp objects is harmful to the package and may cause incorrect dosage of the medication during use. This applies even to such a small and seemingly harmless item as a needle.
When the cleaning of the bottle is completed, you can not immediately use the medication, first you need to calibrate the spray. To do this, double-click on the dispenser bottle. Spray suspensions are sent to the air, not to the nasal mucosa: this is important!
Each new use of the Momat Rino Advance medicine begins with a thorough shake of the bottle.
What can be replaced?
Absolute analogues of āMomat Rino Advanceā are currently not available for sale. There are drugs that contain the same active component as the described medication. These are the trade names:
The analogue (the instruction for Momat Rino Advance is similar to the rules for using this product) Allergodil is known for its good therapeutic effect in case of an allergic reaction. Its main difference is another active component. This medication is based on azelastine.
Allergy: seasonally and year-round
Statistics show that most often, Momat Rino Advance spray and drops are used due to an allergic reaction. If the remedy is used as a preventive measure, and the patient has already reached 12 years of age, then the medication is used once a day, injecting double inhalation into the nasal passage. Total per day a person receives 200 micrograms of the active component. Allergy treatment is done in a similar way.
If the condition of a patient suffering from an allergic reaction improves with Momat Rino Advance, then the volume is halved. This allows you to maintain a therapeutic effect, is not addictive, does not lead to negative effects. In total, in one day the patient should do one injection of the Momat Rino Advance spray in the nasal passage. In total, within 24 hours, 100 Ī¼g of the active substance enters the body.
What to look for?
In some cases, the recommended dose for treatment (200 mcg per day) does not give a pronounced therapeutic effect. The manufacturer indicates in the instructions that, in agreement with the attending physician, you can double the volume of the drug, up to 400 mcg. The drug is also used once a day, but the drug is injected into each nostril four times. When allergy symptoms begin to decrease, the amount of drug used is reduced to a standard therapeutic dose.
The effectiveness of āMomat Rino Advanceā can be seen within half a day after initial use.
Age features
If Momat Rino Advance is used to treat patients aged 2-11 years, then the dose for 24 hours is only 100 mcg. It is introduced into the body in one approach, one spray at a time in the nasal passage. At a young age, the child cannot enter the remedy himself correctly, the help of elders is necessary.
Sinusitis: acute, aggravated chronicles
In these diseases, āMomat Rino Advanceā is used as an auxiliary medication to enhance the therapeutic effect of the course of treatment. Allowed to use at the age of 12 years and older, without the upper limit (use by the elderly is possible). Treatment, prevention of sinusitis (including exacerbation of the chronic) require the use of a suspension twice a day. Two injections are made into the nasal passage. In total, 400 mcg of the active substance enters the body per day.
With the low effectiveness of such a scheme of application, āMomat Rino Advanceā is allowed to double the dose by 24 hours, up to 800 mcg. Twice daily do four inhalations of the suspension. As soon as the pronounced symptoms of the disease disappear, the dose is again reduced to the recommended 400 kg per day.
The acute form of rhinosinusitis, not complicated by severe infection with bacteria
Treatment of this disease with the help of "Momat Rino Advance" is allowed when the patient reaches 12 years. The initial dose is twice a day, two injections in each nasal entrance. If you feel worse, you must consult your doctor to adjust the treatment regimen.
Polyps
If polyposis has been identified, Momat Rino Advance can be used by adults. The initial dosage is two injections into the nasal passage twice a day. For a situation when the symptoms at the indicated concentration of the active substance in the body gradually disappear, the dose is halved: use āMomat Rino Advanceā once every 24 hours, making two inhalations.
Trouble: why be prepared?
In some cases, people who use the Momat Rino Advance spray according to the instructions for use encounter side effects. The negative reactions of the body described below relate to the use of the medication in accordance with the instructions, recommendations of the treating doctor, observing age limits on the admissibility of therapy.
Quite unpleasant phenomena are known from the side of breathing. Up to 10% of patients undergoing Momat Rino Advance therapy experience nosebleeds. As a rule, this accompanies the elimination of polyps and is observed only when the medication is used twice a day. Quite often (up to 10% of cases), patients complain of mucosal irritation, expressed by burning. Sometimes the mucous membrane is covered with small ulcers. Bloody discharge is likely: both bleeding and the separation of mucus stained with an admixture of blood.
Extremely small, but there is a chance of perforation of the nasal septum. There is no exact information about the possibility of this side effect, since doctors do not have enough data to sum up objective statistics.
What else is possible?
In some cases, it is likely that parasites and infections are introduced into the body. The risk is higher when treating with the help of the spray āMomat Rino Advanceā polyps by using the medication twice (per day). In addition, you may experience pharyngitis.
From the side of the central nervous system, the most unpleasant of the possible reactions is a headache. This side effect is quite common, about 10% of those treated have complained about it. The digestive tract reacts with the use of āMomat Rino Advanceā with pharyngeal irritation. This consequence is more common with active treatment of polyps (the use of the drug twice a day).
In some cases, you may encounter a weakening of smell, a violation of the taste buds. Due to the low frequency of cases, there are currently no clear medical statistics on these side effects. It is also not known how large the percentage of deviations from the visual organs is. It is known that those undergoing therapy with the nasal spray āMomat Rino Advanceā have a small risk:
- cataracts;
- glaucoma
- increased pressure inside the eye.