The medicine "Clotrimazole" is a local antifungal drug derived from imidazole. The drug has an effect on various microorganisms. The tool is active against dermatophytes, dimorphic fungi, mold fungi, pathogens of blastomycosis, actinomycetes. Low concentrations of the drug have fungistatic, high - fungicidal effect.
Describing the effect of Clotrimazole (candles), the instructions for use indicate the ability of the drug to slow down the synthesis of ergosterol (the main component in the structure of the membrane of the fungal cell). The absence of this element provokes destructive changes in the membranes of microbial cells. The drug "Clotrimazole" inhibits the activity of peroxidases. This further facilitates the accumulation of hydrogen peroxide in the fungal cell, which also contributes to the destruction.
The medicine "Clotrimazole" has an antibacterial effect on gram-positive microbes, in particular, streptococci and staphylococci, as well as corynebacteria (to a lesser extent). The drug has a trichomonas and anti-amoebic effect.
The medication "Clotrimazole" (suppository) recommends the use of urogenital candidiasis. The indications also include mycosis of the skin, including with secondary infection.
The drug is used in the form of an ointment, solution, spray liquid. The most convenient form in some cases are suppositories (for insertion into the vagina).
With urogenital candidiasis, Clotrimazole (vaginal tablets) (reviews of many patients indicate this) is very effective in combination with cream. After the suppository is introduced into the vagina from the outside, ointment is applied to the genitals and the perineum. In some cases, instillation (instillation) in the urethra of a one percent solution is also carried out for six days.
The drug "Clotrimazole-Acre" (ointment) is used for fungal lesions on the mucous membranes and skin, provoked by dermatophytes, yeast-like and mold fungi. The remedy is indicated for multi-colored lichen, vulvovaginal candidiasis, erythrasma, trichomoniasis. The medication is used before childbirth for the rehabilitation of the birth canal.
Means "Clotrimazole-Acre" (candles) is not available.
Apply ointment per day no more than three times. The duration of treatment is about four weeks (on average). After eliminating the signs of pathology, experts recommend continuing treatment for another two weeks.
With local use of the drug "Clotrimazole" (suppository) (instructions for use contain such data) side effects are extremely rare. In some cases, however, allergic reactions may occur.
The drug "Clotrimazole" (suppository) instructions for use does not allow for the appointment of hypersensitivity. Contraindications include the first trimester of pregnancy.
The effect of the drug on the condition of the newborn and lactating woman has not been studied. In this regard, the advisability of prescribing medication during lactation is determined by the doctor.
Means "Clotrimazole" has the ability to slow down the action of other local antifungal drugs. They include such medicines as Nystatin, Natamycin.
When taking the drug "Dexamethasone" in high doses, the antifungal activity of the agent "Clotrimazole" slows down.
Do not apply ointment to the area near the eyes.
In order to avoid secondary infection, it is necessary to conduct simultaneous treatment of both sexual partners.
The treatment of trichomoniasis is recommended to be carried out in conjunction with chemotherapeutic drugs (with Metronidazole inside, for example).
Before using the medicine "Clotrimazole" you need to consult a doctor.