Sinaflan liniment has anti-inflammatory, anti-allergic, antiexudative and antipruritic properties. When exposed to the skin, a warning process of the marginal accumulation of neutrophils occurs, which leads to a decrease in inflammatory exudate and the production of cytokines. Additionally, inhibition of macrophage migration is observed along with a decrease in granulation and infiltration. Next, we consider in detail the instructions for use of the drug.
Pharmacokinetics
After absorption from the skin surface, Sinaflan liniment binds to plasma proteins, undergoing metabolism, which occurs mainly in the liver. The remedy is removed, usually by the kidneys.
Indications for use of liniment
Sinaflan is a pharmaceutical product that must be used in a number of the following situations:
- In acute and chronic inflammatory and allergic skin diseases, which differ in non-microbial etiology and are accompanied by dry skin.
- In the presence of seborrheic dermatitis or eczema of different genesis and localization.
- Against the background of neurodermatitis.
- In case of skin itching, psoriasis, sunburn, insect bites and so on.
Dosage regimen
Adults and children over two years of age can use this drug exclusively externally. It is applied to a surface previously wiped with a tampon. It should be moistened with antiseptic liquid. Usually a small amount of the drug is used four times a day. Liniment rubbed lightly. The duration of therapy directly depends on the nature of the pathology and is usually from five to ten days, and in the case of a prolonged course of the disease up to twenty-five days.
With a limited lesion, in order to enhance the effect, Sinaflan Liniment ointment can be used under an occlusive dressing. In no case is it permitted to use under a dressing more than 2 grams of the drug composition per day. An ointment is preferable to treat dry forms of dermatoses.
Side effect
Against the background of the use of the considered Sinaflan liniment in patients, such undesirable manifestations can be observed:
- Burning, itching, or dry skin.
- The appearance of steroid acne and folliculitis.
- Perhaps, among other things, the development of a secondary infectious skin lesion and atrophic changes in it.
- With prolonged use, secondary immunodeficiency usually occurs along with hypertrichosis, alopecia, especially in women.
- Atrophy of the integument and hirsutism are not ruled out, and sometimes telangiectasia, purpura, and a violation of the pigmentation process occur in the area of application of the drug.
- In the case of use on a vast surface, a systemic manifestation is possible (gastritis along with a stomach ulcer, adrenal insufficiency, Cushing's syndrome, steroid diabetes and a slowdown in reparative processes).
Contraindications
According to the instructions for use of Sinaflan to the liniment, it is forbidden to use the agent in a number of the following situations:
- In the presence of hypersensitivity.
- In case of cutaneous manifestations of syphilis or tuberculosis.
- With diaper rash, rosacea, and extensive psoriatic plaques.
- Against the background of anogenital itching and infections of the upper cover, which is caused by bacteria, fungi, pyoderma, viruses or chickenpox.
- In the presence of herpes, actinomycosis, blastomycosis, sporotrichosis, trophic ulcers of the lower leg, which is associated with varicose venous expansion.
- In case of erosive and ulcerative lesions of the digestive system.
- In the presence of wounds in areas of applications.
- With skin cancer, atheroma, melanoma, hemangioma, xanthoma, sarcoma.
- Against the background of pregnancy and lactation, as well as in children under two years of age, such a tool can not be used either.
With great caution, the liniment under consideration is used in girls who are in puberty. It is not recommended to use it for treatment for people with an existing atrophic change in the skin, especially in elderly patients. Among other things, it is also worth noting that the total duration of use of this drug in children should in no case exceed five days.
special instructions
In the instructions of the Sinaflan liniment, attention is focused on the fact that the described pharmaceutical agent should be used exclusively in short courses on small areas of the skin. The medication should not be applied to the face. It is also important to avoid contact with eyes. The duration of therapy is determined by the pediatrician, but cannot exceed the period specified in the instructions. During the course, it is recommended to wear loose clothing.
In patients suffering from rosacea or acne vulgaris during therapy, an exacerbation of the current disease is possible. In order to prevent local infectious complications, it is recommended to prescribe this ointment in combination with additional antimicrobial agents.
Overdose
With the onset of such in patients, itching, burning of the skin in the area of application of the ointment may occur, and, in addition, hyperglycemia in combination with glucosuria is not excluded. At the same time, treatment against the background of a gradual withdrawal of the drug is usually symptomatic.
Drug interaction
Sinaflan is a liniment compatible, as a rule, with various medicinal antimicrobial agents. They decrease the activity of antihypertensive, antiarrhythmic and diuretic drugs, as well as potassium preparations. Diuretic pharmaceuticals (other than potassium-sparing) can increase the risk of hypokalemia. During glucocorticosteroid therapy, vaccination with immunization is not recommended, in connection with the immunosuppressive effects of the drug.
What are the conditions for dispensing this product from pharmacies?
The drug is approved for use as a medication over-the-counter medicine. It must be stored in a dry place, in the presence of a temperature of twelve to fifteen degrees, in a place inaccessible to children. Shelf life is usually five years. Do not use the drug in question at the end of the period indicated on the package.
Analogs
The following medicines are referred to substitutes for the described ointment: “Synoderm”, “Flucort” and “Fluocinolone acetonide”. However, the doctor should choose the remedy. Self-medication can lead to negative consequences.
Sinaflan liniment reviews
People in their comments often praise this medical composition. They note that liniment copes well with acute inflammatory and allergic skin diseases, which are distinguished by a non-microbial etiology and are accompanied by dry skin in patients. Satisfied are those patients who used the drug against seborrheic dermatitis, eczema and against the background of neurodermatitis.