Sulfanilamide preparations are a special category of medicines. It consists of different drugs. The choice of this or that remedy depends on the course of the pathology, the pathogen, and also on how the patient transfers certain sulfonamides. Classification involves combining drugs in one group or another in accordance with their pharmacological characteristics.
Medicines of this category are presented in the form of tablets, as well as white or slightly yellowish powders that do not have a smell or taste. Sulfanilamide preparations are poorly soluble in water.
Medicines have an antimicrobial effect. This activity is due to the ability of drugs to disrupt the absorption by microbes of substances important for their development and life.
It is necessary to take sulfanilamide preparations strictly according to the schedule prescribed by the doctor. Premature discontinuation of therapy or the use of drugs in small doses can lead to negative consequences. So, resistant strains of pathogenic microorganisms may appear, which are not further susceptible to the effects of drugs.
Today, various sulfonamides are used in practice. The list of drugs is quite voluminous.
When prescribing a particular drug, it takes into account, among other things, the degree of absorption of the drug from the gastrointestinal tract, the speed and route of excretion, as well as the ability to penetrate into certain tissues and organs.
So, for example, sulfonamide drugs such as Sulfadimezin, Etazol, Norsulfazole, Streptocid, and others are characterized by rapid absorption and the ability to rapidly accumulate in organs and blood in bacteriostatic concentrations. This allows them to be used in the treatment of various pathologies of an infectious nature, provoked by staphylococci, pneumococci, streptococci, meningococci and other cocci, vibrios, protozoa, chlamydia.
Other sulfanilamide preparations, for example, Sulgin and Phtalazole, are absorbed more slowly, are present for a relatively long time in high concentrations in the intestine, excreted mainly with feces. In this regard, such medications are used in the treatment of gastrointestinal pathologies.
If necessary, sulfa drugs can be prescribed in different combinations. So, drugs that are poorly and well absorbed are allowed to be used simultaneously.
When using medications, side effects may occur. In particular, allergic reactions often appear, vomiting, nausea, neuritis, dermatitis and so on occur. Due to the poor solubility, sulfonamides can settle in the form of crystals in the kidneys, clogging the urinary tract. Therefore, when prescribing these drugs, an abundant
alkaline drink is recommended
. Given the spectrum of adverse events, drugs in this group are used only as directed by a doctor. It should be remembered that self-medication can lead to very negative consequences. Before using the prescribed medication, it is necessary to study the annotation.