In the recent past, Adelfan was one of the most common drugs used to relieve symptoms of hypertension. It consisted of two active substances - reserpine and dihydralizine, which had a complex effect. They had the ability to relax the walls of blood vessels, affecting the central nervous system and reducing the number of heart contractions. Why was Adelfan discontinued? And also many people are interested in what now can replace this tool. We will understand this in this article.
Harm to the body
Some effects of the drug are extremely unfavorable for the body. But in the case of sharp jumps in blood pressure of uncertain etymology, Adelfan was indispensable and especially popular among elderly people. Side effects of the drug are quite extensive:
- Oppression of the central nervous system.
- Headaches.
- The development of signs of depression.
- Cramping and cramping.
- Heart failure, angina pectoris and heart attack.
- Irritability.
- Anxiety.
Overdose is very dangerous.
An overdose could lead to speech retardation, drowsiness, dizziness, and slowing down of motor functions. It was impossible to take this drug for epilepsy, pathologies of the heart, liver and kidneys, during pregnancy and at the age of under 18 years. So, why was Adelfan taken out of production?
Safer drugs
Since the drug is obsolete and safer and more modern drugs with a similar effect or more effective entered the pharmaceutical market, it was discontinued at the beginning of 2015, and at the moment it cannot be found in pharmacies.
Pharmaceutical companies have developed a structural analogue that relieves pressure as quickly, but does not have such strong and diverse side effects. Adelfan-Ezidrex, produced in India and almost identical in composition to its predecessor, has been added to this drug, but supplemented with substances that stop the harmful effects of active components. Having the necessary effect in the body, the active substances of the drug are excreted naturally during the next day, not having the ability to negatively affect the internal systems of a person.
Why Adelfan is discontinued is of interest to many.
Dosage
The new drug not only has other properties, but is also taken in other doses. The norm is no more than two tablets per day. However, sometimes one tablet taken in the morning is enough to achieve a stable anti-hypertonic effect. Half an hour after taking it is not recommended to eat. With regular use, the risk of sudden jumps in blood pressure for a long time is reduced.
Contraindications
Contraindications, however, the analogue is not less than the original drug. No less impressive is the list of side effects that can occur in all systems of our body. However, taking Adelfan Ezidrex will help to avoid anemia, dry mouth, upset stools and flushing of the face. This drug is well perceived by organisms in the elderly and patients weakened by other diseases.
Why Adelfan was discontinued is now clear. But how to replace it?
Analogs
In addition to Adelphan Ezidrex, there are other generics. All of them are combined symptoms. That is, they do not remove the root cause of high blood pressure, but only quickly remove the signs of hypertension. Especially often, doctors prescribe the following drugs:
1. "Enap." Inexpensive analogue of "Adelfan", costs only 56 rubles. Lowers blood pressure without slowing down the heart rate. It acts quite softly and is relatively safe.
2. "Triresid". It has the same properties as the previous drug.
3. "Reserpine." It is used not only to relieve symptoms of hypertension, but also for some mental illnesses as part of complex therapy. Released by prescription. Analogs and substitutes "Adelfan" can be bought at any pharmacy.
To relieve symptoms of hypertension
The above drugs have a similar composition, being structural analogues of this drug. However, there are other drugs that relieve the symptoms of hypertension:
1. Apo-Hydro and Dichlothiazide are effective thiazide diuretics. They have a pronounced diuretic effect.
2. “Tenorik”, “Arifon”, “Tenorox” and “Ionik” are thiazip-like diuretics.
3. "Furosemide" and "Lasix" - loop diuretic drugs. They remove excess fluids and salts from the body.
4. “Veroshpiron” refers to diuretics that preserve potassium in the body.
Analogs of the composition "Adelfan" reduce blood pressure due to its pronounced diuretic effect. However, they are strictly contraindicated for those who have problems with the genitourinary system. Treatment with drugs of this group has proven effective along with a relatively small number of side effects and contraindications.
Other generics
Other generics of Adelfan are medicines, the action of which is primarily aimed at solving problems of the cardiovascular system. These include:
1. "Coramin". A fairly well-known analogue, which is prescribed to accelerate the process of restoring myocardial functions in case of ischemia and heart attack. The drug also helps with hypertension, as well as intense stress. "Coramin" is not contraindicated in the elderly, it is prescribed to support the myocardium. To enhance the clinical effect, it is taken in combination with "Vasalamin".
2. Nephrox. A popular Russian analogue of Adelfan. Used for the prevention and treatment of diseases such as high blood pressure, diabetic nephropathy, atherosclerosis, azotemia, renal failure and inflammation in the genitourinary system.
3. “Cordaflex” is prescribed for the treatment of hypertension of various degrees of severity, with ischemia of the heart and angina pectoris. This drug quickly and effectively stops the hypertensive crisis.
4. “Cristal” is prescribed as a prophylaxis and treatment of ischemia, atherosclerosis, arterial hypertension, obliterating endarteritis, and dyscirculatory encephalopathies. Analogs of Adelphan of the new generation are now very popular.
5. "Verapamil." It is also prescribed for hypertension, ischemia and angina pectoris. Suitable for atrial fibrillation and flutter and supraventricular tachycardia. To stop a hypertensive crisis, the drug is prescribed as an injection. It has been proven effective in acute coronary insufficiency and other similar conditions.
6. "Atherophyton". It consists of biologically active components that restore the normal level of cholesterol in the blood and strengthen the walls of blood vessels. It has a preventive effect, preventing atherosclerosis, ischemia, heart failure, varicose veins and thrombophlebitis.
7. "Ebrantil." A worthy alternative to Adelphan. It is produced in the form of a solution for parenteral use. Suitable for relieving hypertensive crisis. Sometimes used as a means of controlling blood pressure during operations. There are other drugs analogues of "Adelfan."
8. The complex "AngiOmega". Dietary supplement containing niacin, vitamin E, omega-3,6,9 acids, policosanol and oleuropein. This dietary supplement is recommended for the prevention and treatment of atherosclerosis, ischemia, angina pectoris and brain diseases such as impaired memory and attention, forgetfulness and cerebral atherosclerosis. In addition, AngiOmega has a supportive effect as part of complex therapy for diabetes, hypertension, low-calorie diet, psycho-emotional stress, decreased immunity, etc.
We figured out why Adelfan was discontinued. Drugs analogues of the described drugs are given in large quantities. But all prescription drugs should be carried out by a doctor.