Antibiotics have long been used to combat serious pathologies. In most cases, it is impossible to cope with serious infectious diseases without them. One such drug is Ampiside. Analogs of this medication can act due to the same basic substance. However, before using them, you need to consult a doctor.
general characteristics
So, "Ampiside" (reviews about it you will read later) is a bactericidal combination drug that kills gram-positive and gram-negative bacteria.
Since most known pathogenic microorganisms have already developed immunity to ampicillin, sulbactam is introduced into its composition to increase the effectiveness of the antibiotic. This component increases the bactericidal properties of ampicillin.
The main active ingredient of Ampisid is 375 mg of sultampicillin. Additional substances are magnesium stearate, carboxymethyl starch, microcrystalline cellulose.
Forms of release and cost of the drug
Ampiside (analogues of the drug can also not be used at its discretion) can be made in this form:
- White or yellowish powder for dilution of suspension. The prepared liquid is taken orally. This product contains 250 mg of active ingredient per 5 ml. The powder is placed in a dark glass bottle with a capacity of 40 or 70 ml. Most often in the package there is a measuring spoon.
- A substance for the preparation of a solution that will be administered intravenously or intramuscularly.
- Pills coated with a special coating that reduces the negative effect of the drug on the esophagus. They have a white or yellow color, as well as a capsule shape.
As for the cost of the medicine, it varies from 190 to 370 rubles. It all depends on the form of release and the concentration of the substance. You can store the product for 2 years. At the same time, the drug should be kept in a closed bedside table, where there is no access to light and children, at a temperature of no more than +25 degrees.
Pharmacological action and drug interaction
Ampiside (suspension) creates difficulties for cell division of pathogenic microorganisms. The active substance is well absorbed in the digestive tract. The highest concentration of a substance in the blood is reached in an hour or two. The half-life of the drug may slow down in infants and the elderly. In the tissues, the antibiotic is distributed evenly. Most of it is removed from the body with urine.
During treatment with this drug, the doctor should constantly monitor the activity of the blood and liver. Such drugs as Phenylbutazone, diuretics can increase the concentration of ampicillin. Ampiside is able to reduce the effectiveness of oral contraceptives. The absorption of the drug increases ascorbic acid, and reduces food and laxatives.
It should be noted that the medication is incompatible with blood products.
Indications
Ampiside (the price of other drugs in the same group may be lower) can be used regardless of the patient's age, even for the treatment of newborns. Especially often it is prescribed to children. There are such indications for taking the drug:
- Infectious pathologies of ENT organs (sinusitis, otitis media, epilotitis) and respiratory tract.
- Bacterial inflammation of the lungs.
- Infectious damage to the kidneys and urinary tract: cystitis, urethritis.
- Cholecystitis.
- Inflammatory diseases of the skin and soft tissues.
- Gonococcal pathology.
- Infectious lesions of internal organs, bones and joints.
- Sepsis, peritonin, meningitis.
- Prevention of the development of infectious complications after surgical interventions.
Contraindications
Like Ampiside itself, its analogues can also not always be accepted. There are such contraindications to the use of the drug:
- Hypersensitivity of the patient to some components of the drug.
- The period of breastfeeding.
- Lymphomycosis.
- Infectious mononucleosis.
- Positive allergy test.
Very carefully, pregnant women and people with kidney failure should use the substance.
What adverse reactions are possible?
The presented medicine may provoke the development of some undesirable effects. It:
- Nausea and vomiting, diarrhea.
- Allergic skin reactions, rash, itching, anaphylactic shock.
- Leukopenia, thrombocytopenia, anemia.
- Candidiasis.
- Possible pain during the injection.
Methods of administration and dosage features
There are several ways to use the drug: oral, intravenous and intramuscular. The dosage of the drug depends on the severity of the pathology, the age of the patient and the type of disease. The most commonly used is Ampiside for children. The instruction provides for the features of taking the medicine for both small and adult patients:
- If the drug is prescribed intravenously, then the course of treatment should not be more than 7 days. An antibiotic can be administered by stream or by dropper. If intravenous administration is not necessary, then therapy with intramuscular injections can be continued.
- The dose of the drug depends on the severity of the disease: with mild - 1.5-3 g / day twice a day, with moderate - 3-6 g per day three times a day, with severe - up to 12 g / day in 4 divided doses.
- For the prevention of postoperative complications during anesthesia, a single dose of an antibiotic in the amount of 1.3-3 g is prescribed before the intervention, then during the day the patient needs to enter the same rate every 6-8 hours.
- If the mass of the child does not exceed 35 kg, then the daily norm does not exceed 50 mg / kg. Divide this dose by 2-3 times. If the medicine is prescribed for a newborn baby, then this dose should be given every 12 hours.
The course of therapy usually lasts about 5 days - 2 weeks. After the symptoms of the pathology disappear and the body temperature returns to normal, the drug should be taken for at least another two days.
It must be borne in mind that it is impossible to prepare a suspension in advance. It is better to do this immediately before use. To do this, add 2-4 ml of water for injection into the powder bottle. You can use boiled water. If the medicine needs to be administered intramuscularly, then a 0.5% lidocaine solution can be used to dilute it.
Analogs, reviews and special instructions
So, Ampiside (an analogue of this drug may not be suitable for the patient) is an effective enough tool to combat infectious pathologies. However, for some patients, this drug may seem quite expensive. Therefore, on the advice of a doctor, you can use such analogues:
- "Unazin."
- "Augmentin."
- Sulbacin.
- Amoxiclav.
- Oscampicin.
If the drug is prescribed to a pregnant woman, then you need to take it strictly according to the scheme that the doctor will approve. In principle, the medicine does not affect driving, however, being sick, this is still not worth it.
As for the reviews, they are mostly positive. But parents often talk about such a side effect as diarrhea. At a sufficiently high cost, the antibiotic after opening is stored for a short time (about 10 days). In addition, some patients may experience an allergic reaction and addiction. The positive quality of the drug can be considered a pleasant smell and a sweetish taste that children like. Ampiside, reviews of which you have already read, cannot be given to your child without permission, since the consequences can be unpredictable.
Be healthy!