“Retinalamin” is a drug belonging to the group of peptide bioregulators. Its action is aimed at relieving inflammation, restoring vascular permeability, stimulating regeneration processes. According to the instructions “Retinalamin” is widely used in ophthalmology.
Release form and composition
“Retinalamin” is produced in the form of a lyophilisate intended for the preparation of a solution. The medicine has a powdery form of white or slightly yellow. The powder is placed in 5 ml glass vials. A container is a cardboard pack and the cell blisters contained in it.
The powder contains:
- the main active substance is a complex of polypeptide water-soluble retinal fractions of cattle in the amount of 5 mg;
- an auxiliary component is glycine (17 mg).
pharmachologic effect
“Retinalamine” has metabolic properties. Its action is aimed at solving several problems at once:
- increased metabolism of eye tissue;
- acceleration of intracellular protein synthesis;
- normalization of cell membrane functions;
- restoration of energy processes;
- regulation of lipid peroxidation.
As a result of such a therapeutic effect, the following changes occur in the tissues of the eye:
- retinal cellular elements and photoreceptors restore their functions;
- light sensitivity increases;
- dystrophic changes in glial cells are blocked;
- vascular permeability improves;
- accelerated tissue regeneration occurs;
- inflammation is removed.
Pharmacokinetics
The main component of the drug is a complex of polypeptide compounds. For this reason, pharmacokinetic analysis of individual elements cannot be done.
Indications for use
Doctors prescribe Retinalamine treatment for:
- diabetic retinopathy;
- primary compensated open-angle glaucoma;
- central retinal dystrophy (pathology may have a traumatic or inflammatory genesis);
- tapetoretinal abiotrophy (peripheral or central);
- myopia;
- retinal detachment (traumatic or regmatogenous).
Only a doctor can prescribe a medicine. Self-administration is strictly prohibited even if the instructions for use are fully observed. Reviews of “Retinalamine” characterize the drug as effective and easily tolerated.
Application chart
The frequency of administration and duration of the course is chosen by the doctor. In this case, the patient’s diagnosis, age, general condition and concomitant diseases are taken into account.
The drug is taken in two ways:
- parabulbar - in this case, the prepared solution is injected into the lower eyelid region;
- intramuscularly.
To prepare the solution, the contents of one bottle are mixed with 1.2 ml of one of the proposed liquids:
- 0.9% sodium chloride solution;
- water for injections;
- 0.5% solution of procaine (novocaine).
Depending on the severity and type of disease, the dosage of Retinalamin may vary. The instruction recommends the following scheme.
For adult patients, the standard dose is 5 mg of the drug, which is administered 1 time per day. The duration of the course reaches 10 days. In some cases, a repeat course is required after 3-6 months.
Children aged 1 to 5 years are prescribed 2.5 mg of the drug once a day. This regimen is often chosen for atrophy and dystrophy of the retina.
For children from 6 to 18 years, doctors can vary the dosage in the range of 2.5-5 mg of the drug.
Overdose
The official instructions for use "Retinalamin" there is no information about cases of overdose with this drug. Moreover, the recommended therapeutic dose is not recommended to be exceeded.
Side effects
The main active component of Retinalamin (according to the instructions) is a complex of polypeptide water-soluble fractions obtained from animals. This significantly reduces the number of side effects that appear after taking the drug.
Manufacturers warn only about the possibility of allergic reactions. This occurs if the patient is hypersensitive to the composition of the drug. In this case, a rash, redness on the skin and itching may occur. If such symptoms are detected, the drug injections are canceled. If you believe the instructions and reviews about "Retinalamine", such manifestations are rare.
Contraindications
"Retinalamin" is contraindicated in the following circumstances:
- hypersensitivity to the active component;
- period of pregnancy - treatment should be postponed;
- lactation period - if immediate treatment is required, lactation is interrupted (this is done due to the lack of data on the effect of the drug on children);
- children's age up to 1 year.
Caution should be given to children under 18 years of age.
special instructions
The medicinal powder is diluted only with those liquids that are recommended by the manufacturers and are named in the instructions for “Retinalamine”. The use of other liquids is strictly prohibited.
The solution is used immediately after preparation. Keep it prohibited.
If one injection was missed for any reason, administering a double dose is not recommended. The next injection should be carried out according to the treatment regimen using a standard dose.
Unused drugs do not need to be disposed of with special precautions.
Due to the absence of side effects, the drug does not affect the ability to drive a car and other mechanisms.
Analogs
If you read the instructions, there are no analogues of Retinalamin in composition and action, however, with similar diagnoses, you can replace this drug with parabulbar administration of antioxidants. In the list of representatives of this drug group are called “Mildronate” and “Emoxipin”.