Among antibacterial drugs for many years, one of the most popular is Linkomycin. Analogues of the drug, which appeared later, have the same effect and are no less effective. These are narrow-spectrum antibiotics that are active against gram-positive and anaerobic bacteria. Lincomycin belongs to the group of linkcosamides. Allocated these drugs in a separate form because of the specificity of their action.
Features of Lincosamides
This group of antibiotics includes Lincomycin and Clindamycin, its semi-synthetic analogue. They have a special mechanism of action on bacteria. In general, these are drugs that affect protein synthesis in the cells of microorganisms, which prevents their reproduction. This is the so-called bacteriostatic effect. But in high concentrations, the drug "Lincomycin" has a bactericidal effect. Its analogs have the same properties.
They are effective against gram-positive cocci: streptococci, staphylococci, pneumococci. But gram-positive bacteria, fungi, protozoa and viruses cannot destroy Lincomycin. Its analogues, like the drug itself, are prescribed for:
- infections of the skin, bones and joints;
- peritonitis, abscess, furunculosis;
- diseases of the pelvic organs - endometritis, adnexitis, vaginosis;
- tonsillitis, pharyngitis, pneumonia;
- scarlet fever, diphtheria;
- erysipelas, impetigo, acne.
Contraindications and side effects
"Lincomycin" and its analogues are rapidly absorbed in the gastrointestinal tract and after a couple of hours are found in all tissues and environments of the body, including breast milk and bones. Therefore, lincosamides are contraindicated in diseases of the gastrointestinal tract, liver and kidneys, pregnancy and lactation, as well as for individual intolerance.
When using these drugs, the following side effects are possible:
- abdominal pain, nausea;
- allergic reactions, rash, itching, Quincke's edema;
- fever, sore throat;
- candidiasis;
- bleeding disorder.
"Lincomycin": instructions for use
Analogues of the drug have the same composition and mode of action. They can be purchased under several names: "Linkomycin", "Linkomycin hydrochloride", "Tsilimitsin", "Neloren", "Medoglytsin", "Linosin", "Linkotsin". All of these drugs are equally effective against gram-positive bacteria. Especially often they are used against streptococci, which are resistant to other antibiotics.
These drugs are available in tablets or capsules, most often 500 mg each. You need to take them several hours before a meal, since any food greatly reduces the effectiveness of the action. Usually, 3-4 times a medication is prescribed. The duration of treatment is 1-2 weeks. But with complex infections of the skin, soft tissues and bone system, it can be extended up to 3 weeks. Indeed, the resistance of microorganisms to Linkomycin, if it is produced, is very slow.
Features of the use of "Lincomycin" and its analogues
These drugs have long been used in medicine. After all, some microorganisms are insensitive to penicillins and other groups of antibacterial drugs, in this case, Lincomycin is effective. Analogs in tablets are used for sepsis, postoperative complications, osteomyelitis, purulent arthritis, furunculosis, pneumonia.
It has long been used in dentistry. It is more effective than other antibiotics to cope with periodontitis, gingivitis, and prevents the development of caries. The best analogue of Linkomycin in dentistry is the Diplen Denta L patch. It is glued to the affected area of the gums for 6-8 hours, during which the active substances destroy the bacteria.
Only as prescribed by the doctor should take "Linkomycin." Analogues of the drug, like himself, are incompatible with many other drugs, so you should not use them for treatment on your own. It is contraindicated to use "Linkomycin" in conjunction with cephalosporins, aminoglycosides, muscle relaxants, barbiturates, "Theophylline" and some other drugs.
"Lincomycin" (ointment): analogues
The drug is also available for external use. In the form of ointment, it is used in the treatment of purulent-inflammatory skin diseases. Available under the name "Lincomycin Akos". This ointment is effective in the treatment of pyoderma, furunculosis, phlegmon, erysipelas, acne. The drug should be applied in a thin layer to the affected area 2-3 times a day. It is advisable not to use the ointment if the inflammation is complicated by a fungal infection.
To prevent wound infection during surgical operations and dental interventions, "Lincomycin Films" are used. These are special sterile wipes saturated with an antibiotic solution.
The therapeutic gel based on clindamycin - "Dalacin" has a similar effect. It is effective for acne. But most often the drug is used for vaginal infections. There is another remedy containing clindomycin - this is Klindavid, which is effective against acne.
There are other antibacterial ointments that have a similar effect. They need to be used if there is intolerance to lincosamides. These are Levomekol, Tetracycline Ointment, Bactroban, Metronidazole and others.
The drug "Clindamycin"
This is a semi-synthetic analogue of Linkomycin. "Clindamycin" is the second representative of the group of linkosamides. It is available in the form of capsules, granules for suspension and injection. “Clindamycin” can be purchased under the following names: “Dalacin”, “Klimitsin”, “Klindafer”, “Clinoxine”. These are newer drugs of the lincosamide group, devoid of some disadvantages:
- they are more active against bacteria;
- better and faster absorbed from the gastrointestinal tract;
- their effectiveness does not depend on food intake;
- they are active against protozoa; therefore, they are often used in the treatment of chlamydia and other vaginal infections.
But "Clindamycin" often causes such a side effect as pseudomembranous colitis. In addition, it costs much more - 130-150 rubles.
Reviews on the use of lincosamides
For many years, Lincomycin has been popular. Its analogs are also known and also common. Low cost - about 40-50 rubles, efficacy against severe infections and a small number of contraindications often make lincosamides the drugs of choice in treatment. Especially a lot of positive reviews about the use of "Linkomycin" and its analogues after tooth extraction. Patients note that the wound quickly healed, but there was no inflammation. Effectively prevents infection of this drug after fractures and soft tissue lesions.
There are also negative reviews about taking lincosamides. Most often, the development of side effects is noted: diarrhea, abdominal pain, allergic rashes. But basically this happens with individual intolerance. To prevent this, along with taking an antibiotic, you need to drink drugs that normalize the intestinal microflora.