Zelboraf tablets are an antitumor drug that is an inhibitor (that is, a substance that suppresses the formation processes) of serine-threonine kinase. This enzyme is known as a regulator of many cellular processes, including as a catalyst for the development of cancerous tumors.
Zelboraf is prescribed for patients suffering from inoperable melanoma with a mutation in the BRAF gene that causes the production of activated protein. The named drug was developed specifically to block this gene and is often successfully used as monotherapy.
Where can I buy Zelboraf cheaper?
It's no secret that drugs for the treatment of cancer are, unfortunately, very expensive. So, in Russia, on “Zelboraf” the price is in the range from 115,000 to 120,000 rubles. But what should a person do who cannot pay the proposed amount for his vital means? A well-proven site will come to the rescue in this case. offering generics of famous brand name drugs.
The generic "Zelboraf" price is much lower than the branded drug, but this is not due to poor quality! Both the composition and effectiveness of the funds are similar. Just a well-known Indian company that bought the right to manufacture these anticancer pills did not invest in development, research and advertising, which influenced such a significant difference in cost.
Dosage and medication
Treatment with the described agent should be carried out only under the supervision of a specialist. To prescribe Zelboraf tablets, the instructions to which are brought to your attention, a mandatory test is performed for the presence of the pathological gene BRAF V600.
The recommended dose is usually 960 mg (4 tablets) at a time. Take the drug twice a day, regardless of the meal time. Although prolonged fasting and the first and second doses should be avoided.
You can not chew tablets. Drink better with water.
If the next dose of Zelboraf tablets was missed for any reason, you can drink them later, but with an interval between doses of 4 hours or more. It is impossible to take both doses at once. If the next intake of tablets caused vomiting, then you should not drink them additionally. Continue treatment as usual.
To whom the drug is contraindicated
"Zelboraf" is not prescribed to patients who have certain contraindications to the use of the described medication. These include:
- patients suffering from severe renal and hepatic insufficiency;
- patients with impaired water and electrolyte balance, not amenable to correction;
- children and adolescents under the age of 18;
- Pregnant
- nursing;
- suffering from long QT syndrome;
- taking drugs that contribute to lengthening the named interval.
Side effects
During treatment with Zelboraf, the following side effects are most often observed:
- fatigue;
- nausea, upset stool;
- the development of alopecia and papilloma of the skin;
- decreased appetite and weight;
- distortion of taste;
- headache;
- dizziness;
- peripheral neuropathy;
- dry skin
- increased sensitivity to ultraviolet radiation;
- muscle and bone pain;
- peripheral edema.
All of these manifestations must be reported to the attending physician in order to avoid undesirable consequences.