According to the instructions for use, Essential in ampoules is a drug from the group of hepatoprotectors, which contains natural phospholipids that are constantly needed by the body from the outside, since such compounds cannot be synthesized in its cells. These elements are called essential. They can be compared with the necessary amino acids, which are constantly required by the human body and must come from food.
Therapeutic effects of the drug "Essentiale"
The therapeutic effect of all varieties of Essential is determined by its phospholipids. Vitamins in the composition of the drug can not only enhance the effects of these important components, but also make up for their deficiency in organs and tissues. Thus, vitamins play a significant role in the main therapeutic effect of the drug in question. In order for readers to have an idea of āāhow this drug should look like, we provide a photo of Essential in ampoules. Instructions for use in this article we will consider with all the details.
To begin with, we note that phospholipids, which are part of Essential, normally act as substances that make up the structure of the cell membrane. Phospholipids themselves are complex organic compounds that have a short āheadā of phosphatidylcholine and long tails of unsaturated fatty acids such as linolenic and oleic. It is worth mentioning that in their structure phospholipids resemble sperm, only in contrast to them they have two tails, which are composed of fatty acids. Instructions for use with "Essential" in ampoules tell in sufficient detail about the principle of their action for liver health.
So, phospholipids line up in a row with their ātailsā in the direction of one side, and āheadsā in the direction of the other. After that, two similar rows are connected by ātailsā in such a way that their āheadsā turn out to be inward of the cell, that is, in the cytoplasm, and the second part is deployed in the region of the intercellular space. This is indicated by instructions for use in Essential in ampoules. It is important to note that cats can also be given this drug.
Thus, phospholipids are required for the construction of cell membranes in the human body. In the event that they are missed, the membranes will turn out to be fragile, as a result of which substances unnecessary to them can enter the cells, which will provoke their death. The result of damage to the membrane will be premature cell death. This confirms the instructions for use for Essential in ampoules. The description of the action of the drug can be continued.
Due to the fact that phospholipids after the absorption process in the intestine appear, first of all, in the liver, it is here that they are embedded in the membrane, improving their properties and normalizing the structure. The hepatoprotective effect of the Essential Forte drug in ampoules consists in improving the quality of the cell structure, as well as increasing their endurance. Instructions for use also describe these features of the drug.
Due to the positive effect on the structure of cells, the drug reduces the number of dead liver elements. This helps to normalize the functioning of the body, creating all the prerequisites for its effective work in the future. In other words, Essentiale prolongs the vital activity of cells, providing an improvement in the functioning of the liver for a very long period, until the supply of phospholipids is over and the necessary elements begin to die again in large numbers.
Against the background of the use of this drug, normalization of laboratory parameters of liver functions due to hepatitis, fatty degeneration, cirrhosis is noted, and, in addition, the resistance of cells to toxic effects increases. In addition to normalizing indicators, under the influence of the Essentiale preparation in ampoules (according to the instructions for use), the severity of necrosis and also inflammation occurring in the liver tissues are reduced.
Thus, the effects that the drug has on the liver are expressed in the following results:
- There is a restoration of the integrity of the cell membrane of the liver.
- The normal integrity of the liver cell membrane, as well as its structure, is maintained.
- The activity of membrane enzymes is activated, which ensure the transportation of various substances both in the bowels of the cell and out.
- Lipid and protein metabolism improves.
- The stores of glycogen accumulated in the liver increase.
- The detoxification function of the liver improves, that is, there is an increase in the ability of the liver to neutralize all kinds of toxic substances, in particular medicines. This is confirmed by the instructions for use and reviews for the drug "Essential" in ampoules.
- There is a process of conversion of cholesterol and other fats that can cause atherosclerosis into other less dangerous forms, easily eliminated thanks to cells designed to generate energy.
- The need for the liver in excess energy is reduced.
- The fatty infiltration of hepatocytes is reduced or completely eliminated.
- The risk of sclerosis, fibrosis and cirrhosis of the liver is reduced.
- The chemical-physical properties of bile are normalized, during which its lithogenicity, i.e. the ability of bile to form stones in the bladder, is reduced.
In addition to the effects of a positive effect on the liver, all varieties of the drug Essential Forte in ampoules (instructions for use confirm this) can have the following effects on other organs and systems of the body:
- The size, as well as the total number of atherosclerotic plaques, is reduced due to the normalization of the volume of lipoproteins of both high and low density in the blood due to the "Essential" in ampoules. The instructions for use also mention this important property of the drug.
- Blood flow normalizes, which reduces its viscosity against this background.
- Cholesterol is removed from atherosclerotic plaques.
- The severity of clinical signs of diabetes is reduced.
The good tolerance of the Essentiale drug makes it possible to recommend it for use not only to improve the quality of functions along with the state of the liver, but also as a general strengthening agent, which significantly increases the body's resistance to certain diseases.
How to use the drug correctly
As indicated by the instructions for use, Essential in ampoules is a solution that is used for intravenous administration and contains the same amount of phospholipids - two hundred and fifty milligrams in each ampoule. The injection is administered only intravenously. In no case should you enter it intramuscularly or subcutaneously, as this is very likely to cause irritation.
An adult can enter two ampoules at once. Against the background of mild or moderate severity of various diseases, due to which Essentiale was prescribed, the solution should be administered one or two ampoules per day. If a personās condition is severe, the dosage should be doubled. The maximum possible single dose for adults is two ampoules, and the daily dose is four. This confirms the instructions for use for the capsules "Essential Forte N".
For children aged three to six years, the drug is administered two milligrams of the solution once a day, and for children aged seven to twelve years, you can use a twice as large daily dose. If the daily dosage includes no more than two ampoules, then they are administered at one time. When the daily rate of Essential is four ampoules, they are administered in two each morning and evening. It is advisable to administer the solutions of this drug intravenously for no more than one month, and for further continuation of the course, you should go to the capsule. This is indicated by the "Essential N" in ampoules instructions for use.
Immediately before administration, it is important to dilute the solution from the ampoules in a ratio of one to one with the patientās blood or with a solution of five percent glucose or dextrose. True, a solution of glucose and dextrose can only be used when Essentials cannot be diluted with human blood. It is forbidden to dilute this medicinal product with salt solutions, such as, for example, physiological or Ringer's fluid. In addition, you can not mix the solution of the drug with other drugs in the same syringe.
In the event that Essentialia is diluted with a solution of glucose or dextrose, it is necessary to carefully monitor its transparency during the entire time of administration. If the clouding of the substance is noticeable, then it is necessary to stop its administration by removing the needle from the vein, and discard the remaining drug, the missing amount is then introduced from a new ampoule.
The solution "Essential" is injected by the jet method, do it slowly, with a speed not exceeding one milligram per minute. For the introduction, a site with high-quality veins is selected. The elbow area is best suited. True, if the solution cannot be injected into the veins of the ulnar region, then another area is selected, for example, the back of the feet, or the wrist and so on.
Against the background of acute liver diseases, therapy lasts from one to three months, depending on the personās healing rate. In chronic liver damage, the course of use of "Essential N" in ampoules according to the instructions for use is at least six months. If necessary, repeat the treatment.
Special instructions regarding the medicinal product
Since all varieties of "Essential" contain phospholipids that are obtained from natural soybeans, theoretically they are able to provoke certain allergic reactions. Patients prone to such should be careful when using Essential. At the first manifestations of the development of allergic reactions, you must immediately stop using the drug and consult your doctor.
The solution contains a certain amount of ethanol used in the extraction of phospholipids from beans. The amount of ethyl alcohol is insignificant and does not cause any reactions that are characteristic of alcohol. During the entire period of therapy, it is important to refrain from the use of any substances that adversely affect the liver, for example, alcohol, drugs and so on. This is indicated by the "Essential" in ampoules instructions for use. Contraindications must be taken into account.
Against the background of chronic hepatitis, the drug can be used only if the person's condition improves. For children, it is forbidden to use ampoule solutions for the intravenous method of administration for up to three years. The ban on use at such a young age is associated with the content of benzyl alcohol in the composition of the product, which can provoke the formation of Gaspings syndrome with subsequent death. What else does the instruction for use with Essential N in ampoules tell us?
Side effects
The medication, as a rule, is well tolerated and rarely causes any side effects, however, if they appear, you should immediately stop using this medication and consult your doctor.
The side effects of ampoule solutions that are used for intravenous injection include the following symptoms:
- Allergic reactions of the body, such as various rashes, itching and exanthema along with urticaria.
- The appearance of irritation in the injection area.
- Diarrhea against the background of the use of large doses of ampoule solution.
The effect of the drug on the ability to drive a car
Ampules "Essential" do not have any negative impact on the ability of the driver to drive all kinds of mechanisms and the car as well. For this reason, during the entire period of use of this drug, a person can calmly and without fear engage in any activity that requires a high reaction rate, as well as concentration.
This describes the instructions for use for the medicine "Essential" in ampoules.
Overdose
Over the entire period of observation of the clinical use of the drug, an overdose was never recorded. True, according to theoretical information, an overdose symptoms are an increase in the manifestation of possible side effects.
In order to eliminate the symptoms of an overdose, you should completely stop taking the medicine and conduct symptomatic therapy, which will be aimed at maintaining the normal activity of vital human organs.
Instructions for use of analogues to "Essential" in ampoules do not describe, we will consider them below.
Interaction "Essential" with other drugs
An ampoule solution for intravenous administration is able to interact with anticoagulants, that is, substances that reduce blood coagulation, while enhancing their effect. For this reason, within the framework of the simultaneous use of these products, it is desirable to reduce the dosage of the anticoagulant.
Analogs
Due to the fact that the main active ingredient of the drug is phospholipids, other drugs that contain the same substances as their active components will also be analogues of this drug. True, some drugs besides phospholipids also contain vitamins. Thus, medications that contain only phospholipids serve as analogues of Essential N and Essential Fort N. And those of them that include phospholipids and a vitamin complex in their composition are analogues of Essential and Essential Forte. Instructions for use indicate which analogues can be used.
The pharmaceutical market offers a wide range of all kinds of Essentiale analogs, which include drugs from the hepatoprotective category, in which the active ingredients do not contain phospholipids, but other substances that have the most similar list of effects, as well as therapeutic effects.
Thus, the following medicinal products act as analogues of Essential Forte N in ampoules (instructions for use are in each package):
- "Bongigar" in capsules and in the form of syrup.
- Dipana in tablet form.
- Dragee "Carsil".
- Solution for injections "Laennec".
- "Hepafit" in the form of a plant collection for the preparation of infusions.
- Solution for injection "Metrop GP".
- Capsules "Progepar".
- "Rosilimarin" in tablets.
- Capsules, rectal suppositories, as well as Tykveol oil.
- Capsules "Cholenol".
- Solution and tablets "Elkar".
These are all analogues of Essential in ampoules. Instructions for use and reviews are of interest to many.
Among the counterparts to the cheapest, the cost of which does not exceed three hundred rubles, include the following products:
- Livolife Fort.
- "Antraliv."
- "Brenziale forte."
- Essliver.
Recognized as the most bought, as well as cheap counterparts are the drugs "Liv 52" and "Karsil".
According to the instructions for use, Essential Forte N in ampoules is a medicine from the category of hepatoprotectors, which is designed to maintain the healthy functioning of the liver, and in addition, prevent the occurrence of cirrhosis due to chronic diseases of this organ. Essentiale perfectly copes with the tasks assigned to it and provides an improvement in the patientās well-being after regular courses of treatment. True, like other drugs, it does not serve as universal and perfectly suitable for absolutely everyone. That is why the question of which medicines are better than Essential, from the point of view of specialists, is not correct.
To answer this question, you should know all the features, as well as the reactions of a person to all kinds of drugs from the category of hepatoprotectors. Only then will it be possible to determine the group of drugs that are best suited to the patient.Then it is necessary to trace which drug has the greatest possible therapeutic effect, without causing side effects. It is this drug that will serve as the best therapeutic agent for this particular patient.
Thus, it is impossible to answer in general which medications will be better than Essential, meaning all patients who suffer from liver diseases, as each personās body is individual. On the whole, Essential is one of the best hepatoprotectors available on the pharmaceutical market.
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Reviews
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Negative reviews about Essential are quite few in number and are due to two main factors - the lack of the expected clinical result or the consumers' conviction that this drug is a relatively old remedy, since at the moment there are much more effective hepatoprotectors.
We have reviewed the instructions for use for the Essential drug in ampoules.